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I P Shanura Fernando

Explore the profile of I P Shanura Fernando including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 20
Citations 464
Followers 0
Related Specialties
Biochemistry
Biology
Toxicology
Top 10 Co-Authors
You-Jin Jeon
Won Woo Lee
K K Asanka Sanjeewa
Hyun-Soo Kim
Thilina U Jayawardena
Seo-Young Kim
Lei Wang
Dae-Sung Lee
Ginnae Ahn
Seung-Hong Lee
Published In
Int J Biol Macromol
EXCLI J
Environ Toxicol Pharmacol
J Med Food
Ecotoxicol Environ Saf
Affiliations
Soon will be listed here.
Recent Articles
1.
3β-Hydroxy-Δ5-steroidal congeners from a column fraction of attenuate LPS-induced inflammatory responses in RAW 264.7 macrophages and zebrafish embryo model
Fernando I, Lee W, Jayawardena T, Kang M, Ann Y, Ko C, et al.
RSC Adv . 2022 May; 8(33):18626-18634. PMID: 35541104
Bioactive compounds from marine organisms and their action mechanisms have provided new insights into medicinal and natural product research. Here, we report the identification of 3β-hydroxy-Δ5-steroidal congeners from a purified...
2.
Eckol from Ecklonia cava ameliorates TNF-α/IFN-γ-induced inflammatory responses via regulating MAPKs and NF-κB signaling pathway in HaCaT cells
Cho S, Kim H, Lee W, Han E, Kim S, Fernando I, et al.
Int Immunopharmacol . 2020 Feb; 82:106146. PMID: 32088638
We investigated the protective effect of the bioactive compound eckol on inflammatory-related skin lesions in vitro. HaCaT cells were stimulated with tumor necrosis factor-alpha (TNF-α) and interferon-gamma (IFN-γ) mixture, and...
3.
Fucoidan isolated from Padina commersonii inhibit LPS-induced inflammation in macrophages blocking TLR/NF-κB signal pathway
Sanjeewa K, Jayawardena T, Kim H, Kim S, Fernando I, Wang L, et al.
Carbohydr Polym . 2019 Sep; 224:115195. PMID: 31472848
Brown seaweeds are well-known source of bioactive compounds, which are producing a variety of secondary metabolites with promising bioactive properties. Traditionally, seaweeds used as ingredients in medicine for many centuries...
4.
A keratinocyte and integrated fibroblast culture model for studying particulate matter-induced skin lesions and therapeutic intervention of fucosterol
Fernando I, Jayawardena T, Kim H, Vaas A, De Silva H, Nanayakkara C, et al.
Life Sci . 2019 Aug; 233:116714. PMID: 31376370
Increased levels of particulate matter (PM) air pollutants in East Asia have resulted in detrimental health impacts increasing morbidity and mortality. Epidemiological studies suggest a possible relation between the cutaneous...
5.
Free radical scavenging activity of the peptide from the Alcalase hydrolysate of the edible aquacultural seahorse (Hippocampus abdominalis)
Kim H, Kim S, Fernando I, Sanjeewa K, Wang L, Lee S, et al.
J Food Biochem . 2019 Jul; 43(7):e12833. PMID: 31353700
Seahorses, Hippocampus abdominalis, have a long history in traditional Chinese medicine as an important healthy ingredient in foods. This study evaluated the antioxidant activity of an enzymatic hydrolysate prepared from...
6.
Isolation and purification of fucoidan fraction in Turbinaria ornata from the Maldives; Inflammation inhibitory potential under LPS stimulated conditions in in-vitro and in-vivo models
Jayawardena T, Fernando I, Lee W, Sanjeewa K, Kim H, Lee D, et al.
Int J Biol Macromol . 2019 Mar; 131:614-623. PMID: 30898597
Fucoidan, referred to as fucose containing sulfated polysaccharides (FCSP), is a polymer from brown algae cell wall that is reported to exhibit potential anti-inflammatory activity. In the present study, the...
7.
Beijing urban particulate matter-induced injury and inflammation in human lung epithelial cells and the protective effects of fucosterol from Sargassum binderi (Sonder ex J. Agardh)
Fernando I, Jayawardena T, Kim H, Lee W, Vaas A, De Silva H, et al.
Environ Res . 2019 Feb; 172:150-158. PMID: 30782534
Particulate matter (PM) air pollution has gradually become a widespread problem in East Asia. PM may cause unfamiliar inflammatory responses, oxidative stress, and pulmonary tissue damage, and a comprehensive understanding...
8.
Antioxidant and anti-inflammatory functionality of ten Sri Lankan seaweed extracts obtained by carbohydrase assisted extraction
Fernando I, Sanjeewa K, Samarakoon K, Lee W, Kim H, Ranasinghe P, et al.
Food Sci Biotechnol . 2018 Nov; 27(6):1761-1769. PMID: 30483441
Enzyme-assisted extraction is a cost-effective, safe, and efficient method to obtain bioactives from plant materials. During this study, 10 different marine algae from Sri Lanka were individually extracted by using...
9.
Sargassum horneri (Turner) C. Agardh ethanol extract inhibits the fine dust inflammation response via activating Nrf2/HO-1 signaling in RAW 264.7 cells
Jayawardena T, Sanjeewa K, Fernando I, Ryu B, Kang M, Jee Y, et al.
BMC Complement Altern Med . 2018 Sep; 18(1):249. PMID: 30200963
Background: Among the different kinds of pollution, air pollution continues to increase globally. East Asia is considered to be significantly affected. As a result, the populations in these regions face...
10.
Apoptotic and antiproliferative effects of Stigmast-5-en-3-ol from Dendronephthya gigantea on human leukemia HL-60 and human breast cancer MCF-7 cells
Fernando I, Sanjeewa K, Ann Y, Ko C, Lee S, Lee W, et al.
Toxicol In Vitro . 2018 Jul; 52:297-305. PMID: 30012480
The genus Dendronephthya encompasses marine soft corals that produce a wide spectrum of biofunctional terpenoids. Anticancer properties of these metabolites are widely exploited as potential chemotherapeutic agents. The present study...