I J Fidler
Overview
Explore the profile of I J Fidler including associated specialties, affiliations and a list of published articles.
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478
Citations
14316
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Recent Articles
1.
Tanaka T, Godin B, Bhavane R, Nieves-Alicea R, Gu J, Liu X, et al.
Int J Pharm
. 2010 Oct;
402(1-2):190-7.
PMID: 20883755
Porous silicon (pSi) is being extensively studied as an emerging material for use in biomedical applications, including drug delivery, based on the biodegradability and versatile chemical and biophysical properties. We...
2.
Mathew P, Thall P, Wen S, Bucana C, Jones D, Horne E, et al.
Br J Cancer
. 2008 Oct;
99(9):1426-32.
PMID: 18841158
In a placebo-controlled randomised study of the platelet-derived growth factor receptor (PDGFR) inhibitor imatinib mesylate and docetaxel in metastatic prostate cancer with bone metastases (n=116), no significant differences in progression-free...
3.
Yazici S, Kim S, Busby J, He J, Thaker P, Yokoi K, et al.
Prostate
. 2005 Jun;
65(3):203-15.
PMID: 15948138
Background: Androgen-independent prostate cancer (PCa) may be susceptible to modulation of the tumor microenvironment. We determined whether a dual tyrosine kinase inhibitor (AEE788) of the epidermal growth factor receptor (EGF-R)...
4.
McCarty M, Bielenberg D, Nilsson M, Gershenwald J, Barnhill R, Ahearne P, et al.
Melanoma Res
. 2003 Jul;
13(4):379-87.
PMID: 12883364
The aim of this study was to determine whether epidermal hyperplasia overlying cutaneous human melanoma is associated with increased tumour angiogenesis, tumour growth and the potential for metastasis. Forty-two surgical...
5.
Solorzano C, Baker C, Bruns C, Killion J, Ellis L, Wood J, et al.
Cancer Biother Radiopharm
. 2002 Jan;
16(5):359-70.
PMID: 11776753
Since vascular endothelial growth factor (VEGF) plays a major role in tumor angiogenesis, we determined whether blockage of VEGF receptor signaling using a novel tyrosine kinase inhibitor (PTK 787) decreases...
6.
Baker C, Solorzano C, Fidler I
Int J Clin Oncol
. 2001 Nov;
6(2):59-65.
PMID: 11706751
No abstract available.
7.
Kuniyasu H, Abbruzzese J, Cleary K, Fidler I
Int J Oncol
. 2001 Sep;
19(4):681-5.
PMID: 11562741
A histopathology study of 22 pancreatic adenocarcinoma cases revealed that 13 of the patients presented with hyperplastic lesions (atypical and non-atypical hyperplasia, mucous cell hypertrophy, focal epithelial hyperplasia, and ductal...
8.
Kuniyasu H, Yasui W, Pettaway C, Yano S, Oue N, Tahara E, et al.
Prostate
. 2001 Sep;
49(1):19-29.
PMID: 11550207
Background: We determined whether treatment of metastatic prostate cancer cells with doxorubicin (DOX) and interferon-alpha (IFN-alpha) prevented the emergence of highly undifferentiated tumor cells. Methods: The state of cell differentiation...
9.
Solorzano C, Baker C, Tsan R, Traxler P, Cohen P, Buchdunger E, et al.
Clin Cancer Res
. 2001 Aug;
7(8):2563-72.
PMID: 11489840
We determined the optimal administration schedule of a novel epidermal growth factor receptor (EGFR) protein tyrosine kinase inhibitor (PKI), PKI 166 (4-(R)-phenethylamino-6-(hydroxyl)phenyl-7H-pyrrolo[2.3-d]-pyrimidine), alone or in combination with gemcitabine (administered i.p.)...
10.
Huang S, Pettaway C, Uehara H, Bucana C, Fidler I
Oncogene
. 2001 Jul;
20(31):4188-97.
PMID: 11464285
Since the NF-kappaB/relA transcription factor is constitutively activated in human prostate cancer cells, we determined whether blocking NF-kappaB/relA activity in human prostate cancer cells affected their angiogenesis, growth, and metastasis...