I Ikegaki
Overview
Explore the profile of I Ikegaki including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
60
Citations
579
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Ishiguro M, Kawasaki K, Suzuki Y, Ishizuka F, Mishiro K, Egashira Y, et al.
Neuroscience
. 2012 Jun;
220:302-12.
PMID: 22710066
Thrombolysis with tissue plasminogen activator (tPA) is the only FDA-approved therapy for acute ischemic stroke. However, hemorrhagic transformation, neurotoxicity, and a short treatment time window comprise major limitations for thrombolytic...
2.
Utsunomiya T, Satoh S, Ikegaki I, Toshima Y, Asano T, Shimokawa H
Br J Pharmacol
. 2001 Dec;
134(8):1724-30.
PMID: 11739249
1. The effects of Rho-kinase inhibitor, fasudil, and of a more specific Rho-kinase inhibitor, hydroxyfasudil, on pacing-induced myocardial ischaemia were determined in anaesthetized open-chest dogs. 2. The dogs were subjected...
3.
Sato S, Ikegaki I, Asano T, Shimokawa H
Jpn J Pharmacol
. 2001 Oct;
87(1):34-40.
PMID: 11676196
We studied the antiischemic properties of fasudil, a Rho-kinase inhibitor, in conscious rabbits with coronary vasospasm induced by vasopressin and endothelin. Pretreatment with fasudil (0.3 and 3 mg/kg) attenuated the...
4.
Ikegaki I, Hattori T, Yamaguchi T, Sasaki Y, Satoh S, Asano T, et al.
Eur J Pharmacol
. 2001 Sep;
427(1):69-75.
PMID: 11553365
Long-term inhibition of nitric oxide (NO) synthesis with N(omega)-nitro-L-arginine methyl ester (L-NAME) induces coronary vascular remodeling in rats. To determine the pathogenic mechanism involved in vascular remodeling, we examined the...
5.
Satoh S, Utsunomiya T, Tsurui K, Kobayashi T, Ikegaki I, Sasaki Y, et al.
Life Sci
. 2001 Sep;
69(12):1441-53.
PMID: 11531167
The neuroprotective property and the effects on hemodynamics of hydroxy fasudil, an active metabolite of an antispastic drug, fasudil, were examined. In rats, hydroxy fasudil was found following intravenous infusion...
6.
Shimokawa H, Morishige K, Miyata K, Kandabashi T, Eto Y, Ikegaki I, et al.
Cardiovasc Res
. 2001 Jun;
51(1):169-77.
PMID: 11399259
Objective: We recently demonstrated that Rho-kinase/ROK/ROCK is functionally upregulated at the arteriosclerotic coronary lesions and plays a key role for coronary vasospastic responses in our porcine model with interleukin (IL)-1beta....
7.
Hitomi A, Satoh S, Ikegaki I, Suzuki Y, Shibuya M, Asano T
Life Sci
. 2000 Nov;
67(16):1929-39.
PMID: 11072869
The aim of this study was to investigate the mechanisms of the pathogenesis of hyperviscosity following cerebral ischemia. Focal ischemia was produced by embolic occlusion of the right middle cerebral...
8.
Toshima Y, Satoh S, Ikegaki I, Asano T
Stroke
. 2000 Sep;
31(9):2245-50.
PMID: 10978059
Background And Purpose: The aim of this study was to develop a new model of stroke based on endothelial damage and thrombotic occlusion in a perforating artery, leading to small...
9.
Ikegaki I
Nihon Yakurigaku Zasshi
. 2000 Sep;
116(2):63-9.
PMID: 10976457
Naftopidil, a phenylpiperazine derivative, is a novel alpha 1-adrenoceptor antagonist and is new drug for the bladder outlet obstruction in patients with benign prostatic hyperplasia (BPH). Naftopidil competitively inhibited specific...
10.
Yamamoto Y, Ikegaki I, Sasaki Y, Uchida T
J Cardiovasc Pharmacol
. 2000 Feb;
35(2):203-11.
PMID: 10672851
Endothelin-1 (ET-1) induces severe pathologic conditions such as coronary spasm followed by vasospastic angina pectoris and acute myocardial infarction. The related pathophysiologic mechanisms have remained obscure. Endothelin-1 receptor (ET(A) and...