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I-Ling Lee

Explore the profile of I-Ling Lee including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 1227
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Recent Articles
1.
Iyer G, Tangen C, Sarfaty M, Regazzi A, Lee I, Fong M, et al.
JCO Precis Oncol . 2024 Nov; 8:e2400287. PMID: 39499893
Purpose: Alterations in DNA damage response (DDR) genes, including , have been correlated with response to neoadjuvant cisplatin-based chemotherapy (NAC) in patients with muscle-invasive bladder cancer (MIBC). The SWOG 1314...
2.
McConkey D, Choi W, Shen Y, Lee I, Porten S, Matin S, et al.
Eur Urol . 2015 Sep; 69(5):855-62. PMID: 26343003
Background: Gene expression profiling (GEP) suggests there are three subtypes of muscle-invasive urothelial cancer (UC): basal, which has the worst prognosis; p53-like; and luminal. We hypothesized that GEP of transurethral...
3.
Yen C, Chiang W, Liu S, Lin C, Liao K, Lin C, et al.
PLoS One . 2015 May; 10(5):e0128011. PMID: 26017803
Areca nut (AN) is a popular carcinogen used by about 0.6-1.2 billion people worldwide. Although AN contains apoptosis-inducing ingredients, we previously demonstrated that both AN extract (ANE) and its 30-100...
4.
Wu C, Chang Y, Chang K, Liu Y, Liu H, Lee I, et al.
Cancer Epidemiol Biomarkers Prev . 2014 May; 23(8):1569-78. PMID: 24859869
Background: Oral cavity squamous cell carcinoma (OSCC) is one of the most common cancers worldwide, and its incidence is still increasing. Approximately 50% of patients with OSCC die within 5...
5.
Choi W, Porten S, Kim S, Willis D, Plimack E, Hoffman-Censits J, et al.
Cancer Cell . 2014 Feb; 25(2):152-65. PMID: 24525232
Muscle-invasive bladder cancers (MIBCs) are biologically heterogeneous and have widely variable clinical outcomes and responses to conventional chemotherapy. We discovered three molecular subtypes of MIBC that resembled established molecular subtypes...
6.
Jager W, Horiguchi Y, Shah J, Hayashi T, Awrey S, Gust K, et al.
J Urol . 2013 Mar; 190(4):1404-9. PMID: 23500642
Purpose: KU7 is a popular urothelial carcinoma cell line that was isolated from the bladder of a patient at Keio University in 1980. It has subsequently been widely used in...
7.
Marquis L, Tran M, Choi W, Lee I, Huszar D, Siefker-Radtke A, et al.
Cancer Biol Ther . 2012 Feb; 13(7):477-86. PMID: 22361733
Antimitotics such as taxanes are being considered as alternatives to conventional cisplatin-based chemotherapy in patients with bladder cancer, but the molecular determinants of sensitivity or resistance to these agents in...
8.
Choi W, Shah J, Tran M, Svatek R, Marquis L, Lee I, et al.
PLoS One . 2012 Jan; 7(1):e30206. PMID: 22253920
Background: p63 is a member of the p53 family that has been implicated in maintenance of epithelial stem cell compartments. Previous studies demonstrated that p63 is downregulated in muscle-invasive bladder...
9.
Chiong E, Lee I, Dadbin A, Sabichi A, Harris L, Urbauer D, et al.
Clin Cancer Res . 2011 Mar; 17(9):2863-73. PMID: 21415218
Purpose: We investigated the effect of the mTOR inhibitor RAD001 (everolimus) on human bladder cancer (BC) cells in vitro and in vivo. Experimental Design: The effect of RAD001 on the...
10.
Stone 2nd R, Sabichi A, Gill J, Lee I, Adegboyega P, Dai M, et al.
Cancer Prev Res (Phila) . 2010 May; 3(6):776-86. PMID: 20501863
Transitional cell carcinoma (TCC) of the bladder ranks fourth in incidence of all cancers in the developed world, yet the mechanisms of its origin and progression remain poorly understood. There...