I-Che Chung
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Explore the profile of I-Che Chung including associated specialties, affiliations and a list of published articles.
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15
Citations
258
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0
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Recent Articles
1.
Huang W, Chuang C, Huang Y, Chung I, Chen M, Chuang T, et al.
Respir Res
. 2023 Nov;
24(1):280.
PMID: 37964270
Background: Idiopathic pulmonary fibrosis (IPF) is a chronic fatal disease with limited therapeutic options. The infiltration of monocytes and fibroblasts into the injured lungs is implicated in IPF. Enolase-1 (ENO1)...
2.
Chung I, Huang W, Huang Y, Chen M, Tsai A, Wu P, et al.
Oncol Rep
. 2023 Oct;
50(5).
PMID: 37800625
The involvement of enolase‑1 (ENO1), intracellularly or extracellularly, has been implicated in cancer development. Moreover, anticancer activities of an ENO1‑targeting antibody has demonstrated the pathological roles of extracellular ENO1 (surface...
3.
Chen M, Yuan T, Chuang C, Huang Y, Chung I, Huang W
Mol Cancer Ther
. 2022 Jun;
21(8):1337-1347.
PMID: 35700013
Prostate cancer is one of the most common causes of cancer death in men worldwide, and the treatment options are limited for patients with advanced stages of prostate cancer. Upon...
4.
Cbl Negatively Regulates NLRP3 Inflammasome Activation through GLUT1-Dependent Glycolysis Inhibition
Lin H, Chen Y, Wei Y, Chuang Y, Hsieh S, Hsieh J, et al.
Int J Mol Sci
. 2020 Jul;
21(14).
PMID: 32707731
Activation of the nod-like receptor 3 (NLRP3) inflammasomes is crucial for immune defense, but improper and excessive activation causes inflammatory diseases. We previously reported that Cbl plays a pivotal role...
5.
Chung I, Yuan S, OuYang C, Hu S, Lin H, Huang K, et al.
Cytokine
. 2019 Dec;
127:154951.
PMID: 31837587
Psoriasis is a chronic inflammatory skin disease that affects about 2% of the general population. Activation of the Absent in Melanoma 2 (AIM2) inflammasome is crucial for immune defense, but...
6.
Chung I, Chen L, Tsang N, Chuang W, Liao T, Yuan S, et al.
Mol Cell Proteomics
. 2019 Nov;
19(1):142-154.
PMID: 31723016
We previously reported that tumor inflammasomes play a key role in tumor control and act as favorable prognostic markers in nasopharyngeal carcinoma (NPC). Activated inflammasomes frequently form distinguishable specks and...
7.
Chung A, OuYang C, Liu H, Chao M, Luo J, Lee C, et al.
Cancer Med
. 2019 Jul;
8(11):5116-5127.
PMID: 31328403
Approximately, 25% of nasopharyngeal carcinoma (NPC) patients develop recurrent disease. NPC may involve relatively few genomic alterations compared to other cancers due to its association with Epstein-Barr virus (EBV). We...
8.
Chung I, OuYang C, Yuan S, Lin H, Huang K, Wu P, et al.
Nutrients
. 2019 Mar;
11(3).
PMID: 30823406
Colorectal cancer (CRC) is one of the most common malignancies worldwide. Inflammation contributes to cancer development and inflammatory bowel disease is an important risk factor for CRC. The aim of...
9.
Chung I, Yuan S, OuYang C, Lin H, Huang K, Chen Y, et al.
Cell Death Dis
. 2018 Nov;
9(11):1109.
PMID: 30382081
Activation of the NLRP3 inflammasome is crucial for immune defense, but improper and excessive activation causes inflammatory diseases. We previously reported that Pyk2 is essential for NLRP3 inflammasome activation. Here...
10.
Chung I, OuYang C, Yuan S, Li H, Chen J, Shieh H, et al.
Sci Rep
. 2016 Nov;
6:36214.
PMID: 27796369
The inflammasome adaptor protein, ASC, contributes to both innate immune responses and inflammatory diseases via self-oligomerization, which leads to the activation of the protease, caspase-1. Here, we report that the...