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Hsin-Pai Li

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Articles 28
Citations 714
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Recent Articles
1.
Wu C, Li H, Hsieh C, Lin Y, Yi-Feng Chang I, Chung A, et al.
Cancer Lett . 2025 Jan; 614:217482. PMID: 39842500
Oral cavity squamous cell carcinoma (OSCC), a leading subtype of head and neck cancer, exhibits high global incidence and mortality rates. Despite advancements in surgery and radiochemotherapy, approximately one-third of...
2.
Hsu C, Chang Y, Li H
Biomed J . 2024 May; 48(1):100748. PMID: 38796105
Nasopharyngeal carcinoma (NPC) is a malignant tumor originated from the nasopharynx epithelial cells and has been linked with Epstein-Barr virus (EBV) infection, dietary habits, environmental and genetic factors. It is...
3.
Li H, Huang C, Lui K, Chao Y, Yeh C, Lee L, et al.
Transl Oncol . 2023 Sep; 38:101785. PMID: 37713975
Background: Nasopharyngeal carcinoma (NPC) is associated with Epstein-Barr virus (EBV) infection. To test preclinical NPC drugs, we established two patient-derived xenograft (PDX) mouse models, EBV-positive PDX-B13 and EBV-negative PDX-Li41, for...
4.
Lin C, Wu R, Huang C, Lai C, Chao A, Li H, et al.
Cancers (Basel) . 2021 Dec; 13(23). PMID: 34885073
Conventional treatment of dedifferentiated endometrial carcinoma (DEC)-an uncommon and highly aggressive uterine malignancy-is beset by high failure rates. A line of research that holds promise to overcome these limitations is...
5.
Li H, Huang C, Lui K, Chao Y, Yeh C, Lee L, et al.
Cancers (Basel) . 2021 Jul; 13(12). PMID: 34204797
Background: Nasopharyngeal carcinoma (NPC) involves host genetics, environmental and viral factors. In clinical observations, patients of young and old ages were found to have higher recurrence and metastatic rates. Methods:...
6.
Wu C, Yi-Feng Chang I, Hung J, Liao W, Lai Y, Chang K, et al.
Cell Death Dis . 2020 Sep; 11(9):721. PMID: 32883954
High-level expression of ASC (Apoptosis-associated speck-like protein containing a CARD) leads to lymph node metastasis in OSCC, but the underlying mechanism remains unclear. Here, we show that HIF-1α participates in...
7.
Hsu C, Juang H, Kuo C, Li H, Iang S, Lin S, et al.
Viruses . 2019 Oct; 11(10). PMID: 31614652
Hepatitis delta virus (HDV) RNA forms an unbranched rod-like structure and complexes with the delta antigen (HDAg). Host ADAR1-catalyzed RNA editing at the amber/W site of the small HDAg leads...
8.
Chung A, OuYang C, Liu H, Chao M, Luo J, Lee C, et al.
Cancer Med . 2019 Jul; 8(11):5116-5127. PMID: 31328403
Approximately, 25% of nasopharyngeal carcinoma (NPC) patients develop recurrent disease. NPC may involve relatively few genomic alterations compared to other cancers due to its association with Epstein-Barr virus (EBV). We...
9.
Hsu C, Lui K, Chi L, Kuo Y, Chao Y, Yeh C, et al.
J Exp Clin Cancer Res . 2018 Sep; 37(1):233. PMID: 30236142
Background: Patient-derived xenograft (PDX) tumor model has become a new approach in identifying druggable tumor mutations, screening and evaluating personalized cancer drugs based on the mutated targets. Methods: We established...
10.
Li H, Peng C, Wu C, Chen C, Shih M, Huang M, et al.
J Exp Clin Cancer Res . 2018 May; 37(1):102. PMID: 29747653
Background: Aberrant hypermethylation of cellular genes is a common phenomenon to inactivate genes and promote tumorigenesis in nasopharyngeal carcinoma (NPC). Methods: Methyl binding domain (MBD)-ChIP sequencing of NPC cells, microarray...