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Hye Yun Kim

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Articles 76
Citations 1315
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Recent Articles
1.
Kim S, Yun Kim H, Han J, Kim H, Ku S
PLoS One . 2025 Jan; 20(1):e0317812. PMID: 39869608
Background: The oocyte retrieval is a critical step in assisted reproductive technologies, including in vitro fertilization and fertility preservation. Despite evolving techniques, the optimal aspiration pressure during retrieval remains debatable,...
2.
Kwon H, Kim J, Park I, Ye S, Park M, Yang S, et al.
Chembiochem . 2025 Jan; 26(5):e202400906. PMID: 39837793
Alzheimer's disease (AD) is a progressive neurodegenerative condition characterized by the deposition of amyloid-β (Aβ) peptides, which aggregate into toxic structures such as oligomers, fibrils, and plaques. The presence of...
3.
Yun Kim H, Kim Y
Acc Chem Res . 2024 Nov; 57(22):3266-3276. PMID: 39496112
ConspectusA century ago, German neurologist Alois Alzheimer documented the first case of Alzheimer's disease (AD), illuminating cognitive impairments associated with the presence of abnormal protein clusters, including amyloid plaques and...
4.
Yoon S, Yun Kim H, Park S, Cha M, Kim K, Lee S, et al.
Angew Chem Int Ed Engl . 2024 Sep; 63(51):e202411942. PMID: 39314129
Comprehending early amyloidogenesis is essential for the development of effective therapeutic strategies. In tauopathies like Alzheimer's disease (AD), the abnormal accumulation of tau protein is initiated by pathological tau seeds....
5.
Park S, Shin J, Kim K, Kim D, Lee W, Lee J, et al.
ACS Pharmacol Transl Sci . 2024 Sep; 7(9):2650-2661. PMID: 39296253
Aggregation of misfolded amyloid-β (Aβ) and hyperphosphorylated tau proteins to plaques and tangles, respectively, is the major drug target of Alzheimer's disease (AD), as the former is an onset biomarker...
6.
Chae S, Lee H, Lee H, Kim J, Jeong Y, Lin Y, et al.
J Neuroinflammation . 2024 Aug; 21(1):200. PMID: 39129007
Background: We recently reported that the dopamine (DA) analogue CA140 modulates neuroinflammatory responses in lipopolysaccharide-injected wild-type (WT) mice and in 3-month-old 5xFAD mice, a model of Alzheimer's disease (AD). However,...
7.
Cha M, Kim S, Jung E, Cho I, Park I, Yoon S, et al.
Mol Pharm . 2024 Jun; 21(7):3330-3342. PMID: 38875185
The aberrant assembly of amyloid-β (Aβ) is implicated in Alzheimer's disease (AD). Recent clinical outcomes of Aβ-targeted immunotherapy reinforce the notion that clearing Aβ burden is a potential therapeutic approach...
8.
Park S, Hwang J, Jeong S, Choi Y, Min H, Yun Kim H, et al.
Transl Clin Pharmacol . 2024 Apr; 32(1):63-72. PMID: 38586120
Trial Registration: ClinicalTrials.gov Identifier: NCT06147908.
9.
An J, Kim K, Lim H, Yun Kim H, Shin J, Park I, et al.
Nat Commun . 2024 Feb; 15(1):1004. PMID: 38307843
Amyloid-β (Aβ) oligomers are implicated in the onset of Alzheimer's disease (AD). Herein, quinoline-derived half-curcumin-dioxaborine (Q-OB) fluorescent probe was designed for detecting Aβ oligomers by finely tailoring the hydrophobicity of...
10.
Yun Kim H, Lee J, Kim H, Lee B, Jeong J, Cho E, et al.
Exp Mol Med . 2023 Nov; 55(11):2357-2375. PMID: 37907739
Dopamine neurons are essential for voluntary movement, reward learning, and motivation, and their dysfunction is closely linked to various psychological and neurodegenerative diseases. Hence, understanding the detailed signaling mechanisms that...