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Hye Jung Ihn

Explore the profile of Hye Jung Ihn including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 146
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Recent Articles
1.
Kim J, Im S, Lim J, Hong J, Ihn H, Bae J, et al.
Exp Mol Med . 2024 Dec; 57(1):86-103. PMID: 39741184
DOCK5 (dedicator of cytokinesis 5), a guanine nucleotide exchange factor for Rac1, has been implicated in BMP2-mediated osteoblast differentiation, but its specific role in osteogenesis and bone regeneration remained unclear....
2.
Lee S, Kim J, Ihn H, Choi J, Kwon T, Shin H, et al.
Exp Mol Med . 2024 Nov; 56(11):2436-2448. PMID: 39482539
Fibroblast growth factor 23 (FGF23) plays an important role in phosphate homeostasis, and increased FGF23 levels result in hypophosphatemia; however, the molecular mechanism underlying increased FGF23 expression has not been...
3.
Kim J, Lim S, Ihn H, Kim J, Yea K, Moon J, et al.
Mol Med Rep . 2023 Sep; 28(5). PMID: 37732549
Wear particle‑induced osteolysis is a serious complication that occurs in individuals with titanium (Ti)‑based implants following long‑term usage due to loosening of the implants. The control of excessive osteoclast differentiation...
4.
Lim S, Ihn H, Kim J, Bae J, Kim J, Bae Y, et al.
Anim Cells Syst (Seoul) . 2023 Jan; 27(1):1-9. PMID: 36704446
Regulation of osteoclastogenesis and bone-resorbing activity can be an efficacious strategy for treating bone loss diseases because excessive osteoclastic bone resorption leads to the development of such diseases. Here, we...
5.
Lee Y, Ju H, Park S, Ihn H, Park E, Kim J
Curr Mol Med . 2021 Nov; 22(8):747-754. PMID: 34789124
Objective: The relative balance of osteoblasts in bone formation and osteoclasts in bone resorption is crucial for maintaining bone health. With age, this balance between osteoblasts and osteoclasts is broken,...
6.
Ihn H, Lim J, Kim K, Nam S, Lim S, Lee S, et al.
Int J Mol Sci . 2021 Aug; 22(15). PMID: 34361069
Postmenopausal osteoporosis is closely associated with excessive osteoclast formation and function, resulting in the loss of bone mass. Osteoclast-targeting agents have been developed to manage this disease. We examined the...
7.
Lee S, Ihn H, Park E, Kim J
Int J Mol Sci . 2021 Jul; 22(11). PMID: 34200172
Megakaryocytes (MKs) differentiate from hematopoietic stem cells and produce platelets at the final stage of differentiation. MKs directly interact with bone cells during bone remodeling. However, whether MKs are involved...
8.
Assefa F, Lim J, Kim J, Ihn H, Lim S, Nam S, et al.
Tissue Eng Regen Med . 2020 Nov; 18(2):315-324. PMID: 33145742
Background: This study investigates the effects of a neuropeptide, secretoneurin (SN), on bone regeneration in an experimental mouse model. Methods: The effects of SN on cell proliferation, osteoblast marker genes...
9.
Lim S, Kim T, Ihn H, Lim J, Kim G, Choi Y, et al.
Bioorg Med Chem Lett . 2020 Jul; 30(18):127429. PMID: 32731089
Suppression of differentiation and/or function of osteoclasts is considered an effective therapeutic strategy for osteolytic bone diseases such as periodontitis and osteoporosis. Evidence regarding the health benefits of oolong tea...
10.
Ihn H, Kim J, Lim J, Nam S, Hwang S, Kim Y, et al.
J Cell Physiol . 2020 Jun; 236(1):480-488. PMID: 32537777
Tooth root development occurs through the interaction of multiple growth factors and transcription factors expressed in Hertwig's epithelial root sheath (HERS) and dental mesenchyme. Previously, we demonstrated that bobby sox...