Hussam Jourdi
Overview
Explore the profile of Hussam Jourdi including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
307
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0
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Recent Articles
1.
Park E, Kao H, Jourdi H, van Dijk M, Carrillo-Segura S, Tunnell K, et al.
Biol Psychiatry Glob Open Sci
. 2024 Feb;
4(1):252-263.
PMID: 38298788
Background: Phencyclidine (PCP) causes psychosis, is abused with increasing frequency, and was extensively used in antipsychotic drug discovery. PCP discoordinates hippocampal ensemble action potential discharge and impairs cognitive control in...
2.
Haidar M, Jourdi H, Haj Hassan Z, Ashekyan O, Fardoun M, Wehbe Z, et al.
Neuroscientist
. 2021 Jan;
28(6):552-571.
PMID: 33393420
SARS-CoV-2 infects cells through angiotensin-converting enzyme 2 (ACE2), a ubiquitous receptor that interacts with the virus' surface S glycoprotein. Recent reports show that the virus affects the central nervous system...
3.
Shakkour Z, Issa H, Ismail H, Ashekyan O, Habashy K, Nasrallah L, et al.
Curr Med Chem
. 2020 Aug;
28(12):2369-2391.
PMID: 32787753
Edaravone is a potent free-radical scavenger that has been in the market for more than 30 years. It was originally developed in Japan to treat strokes and has been used...
4.
Abou-El-Hassan H, Sukhon F, Assaf E, Bahmad H, Abou-Abbass H, Jourdi H, et al.
Methods Mol Biol
. 2017 May;
1598:65-99.
PMID: 28508358
Degradomics has recently emerged as a subdiscipline in the omics era with a focus on characterizing signature breakdown products implicated in various disease processes. Driven by promising experimental findings in...
5.
Dossat A, Jourdi H, Wright K, Strong C, Sarkar A, Kabbaj M
Neuroscience
. 2016 Nov;
340:243-257.
PMID: 27816701
In humans, some males experience reductions in testosterone levels, as a natural consequence of aging or in the clinical condition termed hypogonadism, which are associated with impaired cognitive performance and...
6.
Jourdi H, Nawa H
Acta Med Biol (Niigata)
. 2013 Jun;
50(3):107-115.
PMID: 23794785
Different cytokines and growth factors, together with their receptors, are expressed in brain tissue. One such molecule is the basic fibroblast growth factor (bFGF) that has recently been shown to...
7.
Jourdi H, Kabbaj M
PLoS One
. 2013 Mar;
8(2):e57124.
PMID: 23460828
Brain-derived neurotrophic factor (BDNF) plays several prominent roles in synaptic plasticity and in learning and memory formation. Reduced BDNF levels and altered BDNF signaling have been reported in several brain...
8.
Zadran S, Jourdi H, Rostamiani K, Qin Q, Bi X, Baudry M
J Neurosci
. 2010 Jan;
30(3):1086-95.
PMID: 20089917
Calpain is a calcium-dependent protease that plays a significant role in synaptic plasticity, cell motility, and neurodegeneration. Two major calpain isoforms are present in brain, with mu-calpain (calpain1) requiring micromolar...
9.
Jourdi H, Hsu Y, Zhou M, Qin Q, Bi X, Baudry M
J Neurosci
. 2009 Jul;
29(27):8688-97.
PMID: 19587275
Brain-derived neurotrophic factor (BDNF) stimulates local dendritic mRNA translation and is involved in formation and consolidation of memory. 2H,3H,6aH-pyrrolidino[2'',1''-3',2']1,3-oxazino[6',5'-5,4]-benzo[e]1,4-dioxan-10-one (CX614), one of the best-studied positive AMPA receptor modulators (also known...
10.
Namba H, Nagano T, Iwakura Y, Xiong H, Jourdi H, Takei N, et al.
Mol Cell Neurosci
. 2006 Jan;
31(4):628-41.
PMID: 16443372
In the developing neocortex, brain-derived neurotrophic factor (BDNF) exerts a trophic activity to increase the expression and channel activity of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptor subunits. Here, we demonstrate that...