Hunter H Chen
Overview
Explore the profile of Hunter H Chen including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
14
Citations
471
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Parenky A, Wadhwa S, Chen H, Bhalla A, Graham K, Shameem M
AAPS PharmSciTech
. 2021 Mar;
22(3):100.
PMID: 33709236
Intravitreal (IVT) administration of therapeutics is the standard of care for treatment of back-of-eye disorders. Although a common procedure performed by retinal specialists, IVT administration is associated with unique challenges...
2.
Sanchez-Felix M, Burke M, Chen H, Patterson C, Mittal S
Adv Drug Deliv Rev
. 2020 May;
167:66-77.
PMID: 32473188
Despite the increasing trend towards subcutaneous delivery of monoclonal antibodies, factors influencing the subcutaneous bioavailability of these molecules remain poorly understood. To address critical knowledge gaps and issues during development...
3.
Schlesinger E, Bernards D, Chen H, Feindt J, Cao J, Dix D, et al.
Bioeng Transl Med
. 2019 Jan;
4(1):152-163.
PMID: 30680326
Despite years of effort, sustained delivery of protein therapeutics remains an unmet need due to three primary challenges - dose, duration, and stability. The work presented here provides a design...
4.
Jiang X, Zheng Y, Chen H, Leong K, Wang T, Mao H
Adv Mater
. 2010 May;
22(23):2556-60.
PMID: 20440698
No abstract available.
5.
Chen H, Ho Y, Jiang X, Mao H, Wang T, Leong K
Nano Today
. 2010 Feb;
4(2):125-134.
PMID: 20161048
Nanoscale vectors comprised of cationic polymers that condense DNA to form nanocomplexes are promising options for gene transfer. The rational design of more efficient nonviral gene carriers will be possible...
6.
Ho Y, Chen H, Leong K, Wang T
J Vis Exp
. 2009 Aug;
(30).
PMID: 19710626
Advances in genomics continue to fuel the development of therapeutics that can target pathogenesis at the cellular and molecular level. Typically functional inside the cell, nucleic acid-based therapeutics require an...
7.
Ho Y, Chen H, Leong K, Wang T
Nanotechnology
. 2009 May;
20(9):095103.
PMID: 19417478
We present a novel convergence of quantum-dot-mediated fluorescence resonance energy transfer (QD-FRET) and microfluidics, through which molecular interactions were precisely controlled and monitored using highly sensitive quantum-dot-mediated FRET. We demonstrate...
8.
Chen H, Ho Y, Jiang X, Mao H, Wang T, Leong K
Mol Ther
. 2008 Jan;
16(2):324-32.
PMID: 18180773
A major challenge for non-viral gene delivery is gaining a mechanistic understanding of the rate-limiting steps. A critical barrier in polyplex-mediated gene delivery is the timely unpacking of polyplexes within...
9.
10.
Ho Y, Chen H, Leong K, Wang T
J Control Release
. 2006 Nov;
116(1):83-9.
PMID: 17081642
We demonstrate a highly sensitive method to characterize the structural composition and intracellular fate of polymeric DNA nanocomplexes, formed by condensing plasmid DNA with cationic polymers through electrostatic interactions. Rational...