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Huiyan Huang

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Articles 25
Citations 480
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Recent Articles
1.
Kaul A, Hope H, Xu C, Basavalingappa R, Binz S, Boily C, et al.
J Pharmacol Exp Ther . 2025 Mar; 392(2):100054. PMID: 40023606
Aclaris Therapeutics Inc (ATI)-2138 is a novel investigational covalent inhibitor of interleukin-2-inducible T cell kinase (ITK), resting lymphocyte kinase, and Janus kinase 3 (JAK3) in development for the treatment of...
2.
Qian S, Zheng C, Wu Y, Huang H, Wu G, Zhang J
Heliyon . 2024 Aug; 10(15):e34951. PMID: 39144922
Leukemia is a kind of hematopoietic stem cell malignant clonal disease. Drug therapy is the core treatment strategy for leukemia, but the current therapeutic drugs have defects such as low...
3.
Koop K, Yuan W, Tessadori F, Rodriguez-Polanco W, Grubbs J, Zhang B, et al.
Hum Mol Genet . 2023 Aug; 32(21):3063-3077. PMID: 37552066
Rab GTPases are important regulators of intracellular vesicular trafficking. RAB5C is a member of the Rab GTPase family that plays an important role in the endocytic pathway, membrane protein recycling...
4.
Huang H, Pan J, Spielberg D, Hanchard N, Scott D, Burrage L, et al.
Proc Natl Acad Sci U S A . 2022 Feb; 119(6). PMID: 35121658
Pathogenic variants in surfactant proteins SP-B and SP-C cause surfactant deficiency and interstitial lung disease. Surfactant proteins are synthesized as precursors (proSP-B, proSP-C), trafficked, and processed via a vesicular-regulated secretion...
5.
Fan D, Huang H, Wang X, Liu J, Liu B, Yin F
Arch Endocrinol Metab . 2021 Mar; 65(3):269-276. PMID: 33740335
Objective: To investigate the association between plasma Hydrogen Sulfide (HS) levels and visceral fat area (VFA) among Chinese young men. Methods: This cross-sectional study involved 156 Chinese male subjects, aged...
6.
Mi L, Wang L, Li X, She S, Li H, Huang H, et al.
J Psychiatr Res . 2021 Mar; 137:290-297. PMID: 33735719
Schizophrenia (SZ) is characterized by a series of cognitive impairments, including automatic processing impairment of basic auditory information, indexed by mismatch negativity (MMN). Existing studies mainly focus on MMN induced...
7.
Chen J, Mohammad A, Pazdernik N, Huang H, Bowman B, Tycksen E, et al.
PLoS Genet . 2020 Mar; 16(3):e1008650. PMID: 32196486
Stem cell systems are essential for the development and maintenance of polarized tissues. Intercellular signaling pathways control stem cell systems, where niche cells signal stem cells to maintain the stem...
8.
Thomas B, Wight I, Chou W, Moreno M, Dawson Z, Homayouni A, et al.
PLoS One . 2019 Mar; 14(3):e0214257. PMID: 30913273
Due to its ease of genetic manipulation and transparency, Caenorhabditis elegans (C. elegans) has become a preferred model system to study gene function by microscopy. The use of Aequorea victoria...
9.
Zheng H, Jia F, Guo G, Quan D, Li G, Huang H
Zhong Nan Da Xue Xue Bao Yi Xue Ban . 2019 Jan; 43(11):1230-1235. PMID: 30643068
To observe the clinical efficacy of dopamine modulator methylphenidate (MPH) of extended-release formulations (MPH-ER) augmentation of ongoing fluvoxamine treatment in refractory obsessive-compulsive disorder (OCD) and its effects on patient's anxiety...
10.
Zheng H, Jia F, Han H, Wang S, Guo G, Quan D, et al.
Eur Neuropsychopharmacol . 2019 Jan; 29(3):397-404. PMID: 30595354
More effective, tolerable interventions for treatment-refractory obsessive-compulsive disorder (OCD) are needed. Preliminary findings encourage optimism that methylphenidate augmentation may be of benefit in the treatment of OCD. To test modulator...