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Hui Cui

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Articles 214
Citations 1346
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Recent Articles
1.
Lu H, Sun D, Wang Z, Cui H, Min L, Zhang H, et al.
J Med Chem . 2025 Feb; 68(4):4148-4167. PMID: 39948720
Cyclin-dependent kinases 12 and 13 (CDK12/13) safeguard genomic integrity by preferentially regulating gene expression in the DNA damage response (DDR). The CDK12/13-mediated upregulation of DDR genes and pathways significantly contributes...
2.
Xuan P, Qi X, Chen S, Gu J, Wang X, Cui H, et al.
J Chem Inf Model . 2025 Jan; 65(3):1631-1640. PMID: 39865931
As an increasing number of microRNAs (miRNAs) have become biomarkers of various human diseases, prediction of the candidate disease-related miRNAs is helpful for facilitating the early diagnosis of diseases. Most...
3.
Gu J, Zhang T, Gao Y, Chen S, Zhang Y, Cui H, et al.
J Chem Inf Model . 2025 Jan; 65(1):435-445. PMID: 39745733
The human microbiota may influence the effectiveness of drug therapy by activating or inactivating the pharmacological properties of drugs. Computational methods have demonstrated their ability to screen reliable microbe-drug associations...
4.
Xuan P, Wu S, Cui H, Li P, Nakaguchi T, Zhang T
Comput Biol Med . 2024 Nov; 184:109321. PMID: 39522133
Identifying the potential side effects for the interested drugs can help reduce harm to patients caused by drugs in clinical use and decrease the risk of drug development failure. Multiple...
5.
Yan D, Chang B, Li Q, Tang Y, He J, Liu Y, et al.
Bioorg Chem . 2024 Oct; 153:107871. PMID: 39383809
Bioaspermeroterpenoid A (1), the first meroterpenoid with an unprecedented hexadecahydroacephenanthrylene carbon skeleton, together with two analogues bioaspermeroterpenoids B and C (2 and 3) were co-isolated from the biotransformation extract of...
6.
Ye J, Cui H, Liu E, Pei X, Chai M, Sun L, et al.
Int J Pharm . 2024 Sep; 666:124757. PMID: 39332459
In drug delivery systems, a stimuli-responsive linker that attaches a targeting carrier and a cytotoxic payload can be dissociated to release the payload on the target over the action of...
7.
He S, Zou Q, Zhang Q, Luo Y, Yan D, He J, et al.
Chin J Nat Med . 2024 Sep; 22(9):864-868. PMID: 39326980
Three novel sesterterpenoids glasesterterpenoids A-C (1-3), featuring an unprecedented 7-cyclohexyldecahydronaphthalene carbon skeleton, were isolated from the root of Lindera glauca (L. glauca). Their structures were elucidated by quantum chemical calculations...
8.
Xuan P, Xu Z, Cui H, Gu J, Liu C, Zhang T, et al.
Bioinformatics . 2024 Sep; 40(9). PMID: 39292557
Motivation: The microbes in human body play a crucial role in influencing the functions of drugs, as they can regulate the activities and toxicities of drugs. Most recent methods for...
9.
Luo M, He Z, Cui H, Ward P, Chen Y
Comput Biol Med . 2024 Sep; 182:109039. PMID: 39232405
Alzheimer's disease (AD) severely impacts the lives of many patients and their families. Predicting the progression of the disease from the early stage of mild cognitive impairment (MCI) is of...
10.
Zou Q, Wei J, Chen Z, Luo A, He J, Long Y, et al.
Chem Biodivers . 2024 Aug; 21(12):e202401658. PMID: 39143743
Glaucic acid isolated from the root of Lindera glauca, was investigated by the biotransformation methods via the endophytic fungi, resulting in the production of five new glausesquiterpenes A-E (1-5), along...