Huguette Debaix
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Explore the profile of Huguette Debaix including associated specialties, affiliations and a list of published articles.
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29
Citations
1032
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Recent Articles
1.
Morelle J, Marechal C, Yu Z, Debaix H, Corre T, Lambie M, et al.
N Engl J Med
. 2021 Oct;
385(17):1570-1580.
PMID: 34670044
Background: Variability in ultrafiltration influences prescriptions and outcomes in patients with kidney failure who are treated with peritoneal dialysis. Variants in , the gene that encodes the archetypal water channel...
2.
Schlingmann K, Renigunta A, Hoorn E, Forst A, Renigunta V, Atanasov V, et al.
J Am Soc Nephrol
. 2021 Apr;
32(6):1498-1512.
PMID: 33811157
Background: The transepithelial transport of electrolytes, solutes, and water in the kidney is a well-orchestrated process involving numerous membrane transport systems. Basolateral potassium channels in tubular cells not only mediate...
3.
Montiel V, Bella R, Michel L, Esfahani H, De Mulder D, Robinson E, et al.
Sci Transl Med
. 2020 Oct;
12(564).
PMID: 33028705
Pathological remodeling of the myocardium has long been known to involve oxidant signaling, but strategies using systemic antioxidants have generally failed to prevent it. We sought to identify key regulators...
4.
Luciani A, Schumann A, Berquez M, Chen Z, Nieri D, Failli M, et al.
Nat Commun
. 2020 Apr;
11(1):1719.
PMID: 32238804
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
5.
Luciani A, Schumann A, Berquez M, Chen Z, Nieri D, Failli M, et al.
Nat Commun
. 2020 Feb;
11(1):970.
PMID: 32080200
Deregulation of mitochondrial network in terminally differentiated cells contributes to a broad spectrum of disorders. Methylmalonic acidemia (MMA) is one of the most common inherited metabolic disorders, due to deficiency...
6.
Olinger E, Lake J, Sheehan S, Schiano G, Takata T, Tokonami N, et al.
Sci Rep
. 2019 Aug;
9(1):12287.
PMID: 31444371
Uromodulin is a zona pellucida-type protein essentially produced in the thick ascending limb (TAL) of the mammalian kidney. It is the most abundant protein in normal urine. Defective uromodulin processing...
7.
Tokonami N, Olinger E, Debaix H, Houillier P, Devuyst O
Kidney Int
. 2018 Oct;
94(5):882-886.
PMID: 30348305
Uromodulin is produced in the thick ascending limb, but little is known about regulation of its excretion in urine. Using mouse and cellular models, we demonstrate that excretion of uromodulin...
8.
Festa B, Chen Z, Berquez M, Debaix H, Tokonami N, Prange J, et al.
Nat Commun
. 2018 Jan;
9(1):161.
PMID: 29323117
The endolysosomal system sustains the reabsorptive activity of specialized epithelial cells. Lysosomal storage diseases such as nephropathic cystinosis cause a major dysfunction of epithelial cells lining the kidney tubule, resulting...
9.
Corre T, Arjona F, Hayward C, Youhanna S, de Baaij J, Belge H, et al.
J Am Soc Nephrol
. 2017 Nov;
29(1):335-348.
PMID: 29093028
Magnesium (Mg) homeostasis is critical for metabolism. However, the genetic determinants of the renal handling of Mg, which is crucial for Mg homeostasis, and the potential influence on metabolic traits...
10.
Hajarnis S, Yheskel M, Williams D, Brefort T, Glaudemans B, Debaix H, et al.
J Am Soc Nephrol
. 2017 Oct;
29(2):518-531.
PMID: 29021386
microRNAs (miRNAs) are sequence-specific inhibitors of post-transcriptional gene expression. The physiologic function of these noncoding RNAs in postnatal renal tubules still remains unclear. Surprisingly, they appear to be dispensable for...