Hugo I MacDermott-Opeskin
Overview
Explore the profile of Hugo I MacDermott-Opeskin including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
51
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Recent Articles
1.
MacDermott-Opeskin H, Wilson K, OMara M
ACS Infect Dis
. 2023 Mar;
9(4):815-826.
PMID: 36920795
The Gram-negative pathogen is a primary contributor to nosocomial multi-drug-resistant (MDR) infections. To combat the rise of MDR infections, novel features of need to be considered for the development of...
2.
Goodwin R, Docker A, MacDermott-Opeskin H, Aitken H, OMara M, Beer P, et al.
Chemistry
. 2022 Mar;
28(28):e202200389.
PMID: 35293643
We report the synthesis of two [2]rotaxanes containing an interlocked three dimensional binding cavity formed from a pyridinium bis(amide) axle component containing two phenol donors, and an isophthalamide based macrocycle....
3.
MacDermott-Opeskin H, Panizza A, Eijkelkamp B, OMara M
Biochim Biophys Acta Biomembr
. 2022 Mar;
1864(7):183908.
PMID: 35276227
Exogenous polyunsaturated fatty acids (PUFAs) are readily incorporated into the synthesis pathways of A. baumannii membrane phospholipids, where they contribute to reduced bacterial fitness and increased antimicrobial susceptibility. Here we...
4.
MacDermott-Opeskin H, Gupta V, OMara M
Biophys Rev
. 2022 Mar;
14(1):145-162.
PMID: 35251360
The proposition of a post-antimicrobial era is all the more realistic with the continued rise of antimicrobial resistance. The development of new antimicrobials is failing to counter the ever-increasing rates...
5.
Findlay J, Patil K, Gardiner M, MacDermott-Opeskin H, OMara M, Kruger P, et al.
Chem Asian J
. 2022 Feb;
17(6):e202200093.
PMID: 35139260
There is a concerted attempt to develop self-assembled metallo-cages of greater structural complexity, and heteroleptic Pd cages are emerging as prime candidates in these efforts. Most of these are dinuclear:...
6.
Adamson L, Tasneem N, Andreas M, Close W, Jenner E, Szyszka T, et al.
Sci Adv
. 2022 Feb;
8(5):eabl7346.
PMID: 35119930
Protein cages are a common architectural motif used by living organisms to compartmentalize and control biochemical reactions. While engineered protein cages have featured in the construction of nanoreactors and synthetic...
7.
Wilson K, Fairweather S, MacDermott-Opeskin H, Wang L, Morris R, OMara M
J Chem Phys
. 2021 Mar;
154(9):095101.
PMID: 33685172
A coarse-grain model of the epithelial plasma membrane was developed from high-resolution lipidomic data and simulated using the MARTINI force field to characterize its biophysical properties. Plasmalogen lipids, Forssman glycosphingolipids,...
8.
Wilson K, MacDermott-Opeskin H, Riley E, Lin Y, OMara M
Biochemistry
. 2020 Aug;
59(33):3010-3018.
PMID: 32786397
Cell membranes contain incredible diversity in the chemical structures of their individual lipid species and the ratios in which these lipids are combined to make membranes. Nevertheless, our current understanding...