Huey-Hsuan Chang
Overview
Explore the profile of Huey-Hsuan Chang including associated specialties, affiliations and a list of published articles.
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8
Citations
716
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Recent Articles
1.
NEMO is a key component of NF-κB- and IRF-3-dependent TLR3-mediated immunity to herpes simplex virus
Audry M, Ciancanelli M, Yang K, Cobat A, Chang H, Sancho-Shimizu V, et al.
J Allergy Clin Immunol
. 2011 Jul;
128(3):610-7.e1-4.
PMID: 21722947
Background: Children with germline mutations in Toll-like receptor 3 (TLR3), UNC93B1, TNF receptor-associated factor 3, and signal transducer and activator of transcription 1 are prone to herpes simplex virus-1 encephalitis,...
2.
Bisiaux A, Thiounn N, Timsit M, Eladaoui A, Chang H, Mapes J, et al.
J Urol
. 2009 Feb;
181(4):1571-80.
PMID: 19230924
Purpose: We characterized the innate immune response to intravesical bacillus Calmette-Guerin therapy using a systems approach based on proteomic and cytometric screens. Materials And Methods: Blood and urine were collected...
3.
von Bernuth H, Picard C, Jin Z, Pankla R, Xiao H, Ku C, et al.
Science
. 2008 Aug;
321(5889):691-6.
PMID: 18669862
MyD88 is a key downstream adapter for most Toll-like receptors (TLRs) and interleukin-1 receptors (IL-1Rs). MyD88 deficiency in mice leads to susceptibility to a broad range of pathogens in experimental...
4.
Ku C, von Bernuth H, Picard C, Zhang S, Chang H, Yang K, et al.
J Exp Med
. 2007 Sep;
204(10):2407-22.
PMID: 17893200
Human interleukin (IL) 1 receptor-associated kinase 4 (IRAK-4) deficiency is a recently discovered primary immunodeficiency that impairs Toll/IL-1R immunity, except for the Toll-like receptor (TLR) 3- and TLR4-interferon (IFN)-alpha/beta pathways....
5.
Ku C, Picard C, Erdos M, Jeurissen A, Bustamante J, Puel A, et al.
J Med Genet
. 2006 Sep;
44(1):16-23.
PMID: 16950813
Background: About 2% of childhood episodes of invasive pneumococcal disease (IPD) are recurrent, and most remain unexplained. Objective: To report two cases of otherwise healthy, unrelated children with recurrent IPD...
6.
von Bernuth H, Puel A, Ku C, Yang K, Bustamante J, Chang H, et al.
Clin Infect Dis
. 2005 Oct;
41 Suppl 7:S436-9.
PMID: 16237643
Septicemia is a life-threatening condition that may lead to sepsis and even septic shock. This cascade is usually accompanied by a pronounced inflammatory response, leading to high body temperature and...
7.
Puel A, Yang K, Ku C, von Bernuth H, Bustamante J, Santos O, et al.
J Endotoxin Res
. 2005 Sep;
11(4):220-4.
PMID: 16176658
Recently, three human primary immunodeficiencies associated with impaired TLR signalling were described. Anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID), either X-linked recessive or autosomal dominant, is caused by hypomorphic mutations in...
8.
Ku C, Yang K, Bustamante J, Puel A, von Bernuth H, Santos O, et al.
Immunol Rev
. 2005 Jan;
203:10-20.
PMID: 15661018
In vitro nine of 10 known human Toll-like receptors (TLRs) are engaged by well-defined chemical agonists that mimic microbial compounds, raising the possibility that human TLRs play a critical role...