Hubertus Hohenblum
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Explore the profile of Hubertus Hohenblum including associated specialties, affiliations and a list of published articles.
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4
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200
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Recent Articles
1.
Mattanovich D, Gasser B, Hohenblum H, Sauer M
J Biotechnol
. 2004 Sep;
113(1-3):121-35.
PMID: 15380652
It is well established today that heterologous overexpression of proteins is connected with different stress reactions. The expression of a foreign protein at a high level may either directly limit...
2.
Hohenblum H, Vorauer-Uhl K, Katinger H, Mattanovich D
J Biotechnol
. 2004 Apr;
109(1-2):3-11.
PMID: 15063609
The expression of recombinant trypsinogens from different mammalian origins in Escherichia coli typically leads to the formation of insoluble aggregates. This work describes the high level expression of human trypsinogen...
3.
Hohenblum H, Gasser B, Maurer M, Borth N, Mattanovich D
Biotechnol Bioeng
. 2004 Feb;
85(4):367-75.
PMID: 14755554
The expression of heterologous proteins may exert severe stress on the host cells at different levels. Depending on the specific features of the product, different steps may be rate-limiting. For...
4.
Hohenblum H, Borth N, Mattanovich D
J Biotechnol
. 2003 May;
102(3):281-90.
PMID: 12730003
This paper describes the establishment of flow cytometric methods for recombinant Pichia pastoris strains, and their application to a lab scale fed batch fermentation. Using a strain which secretes human...