Huaxian Ma
Overview
Explore the profile of Huaxian Ma including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
226
Followers
0
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Recent Articles
1.
Rodriguez M, Fekry B, Murphy B, Figueroa M, Cheng T, Raber M, et al.
Cancer Med
. 2024 Feb;
13(2):e6949.
PMID: 38334474
Background: Acute myeloid leukemia (AML) with an internal tandem duplication in the fms-like tyrosine kinase receptor 3 gene (FLT3-ITD) is associated with poor survival, and few studies have examined the...
2.
Figueroa M, Ma H, Alfayez M, Morales-Mantilla D, Wang F, Lu Y, et al.
Blood Adv
. 2023 Jul;
7(21):6624-6629.
PMID: 37486624
No abstract available.
3.
Bhattacharya S, Piya S, Ma H, Sharma P, Zhang Q, Baran N, et al.
Mol Cancer Res
. 2023 Feb;
21(6):548-563.
PMID: 36787422
Implications: ULK1 drives a cell-intrinsic adaptive resistance in AML and targeting ULK1-mediated autophagy can synergize with existing and emerging AML therapies to overcome drug-resistance and induce apoptosis.
4.
Aitken M, Malaney P, Zhang X, Herbrich S, Chan L, Benitez O, et al.
NAR Cancer
. 2022 Dec;
4(4):zcac039.
PMID: 36518526
Acute myeloid leukemia (AML) is driven by numerous molecular events that contribute to disease progression. Herein, we identify hnRNP K overexpression as a recurrent abnormality in AML that negatively correlates...
5.
Piya S, Yang Y, Bhattacharya S, Sharma P, Ma H, Mu H, et al.
Leukemia
. 2022 Feb;
36(5):1261-1273.
PMID: 35173274
The NOTCH1-MYC-CD44 axis integrates cell-intrinsic and extrinsic signaling to ensure the persistence of leukemia-initiating cells (LICs) in T-cell acute lymphoblastic leukemia (T-ALL) but a common pathway to target this circuit...
6.
Post S, Ma H, Malaney P, Zhang X, Aitken M, Mak P, et al.
Haematologica
. 2021 Nov;
107(6):1311-1322.
PMID: 34732043
FMS-like Tyrosine Kinase 3 (FLT3) mutation is associated with poor survival in acute myeloid leukemia (AML). The specific Anexelekto/MER Tyrosine Kinase (AXL) inhibitor, ONO-7475, kills FLT3-mutant AML cells with targets...
7.
Ruvolo P, Ma H, Ruvolo V, Zhang X, Post S, Andreeff M
Biochim Biophys Acta Mol Cell Res
. 2020 Jun;
1867(10):118785.
PMID: 32590026
The galectin LGALS1 is a glycan binding protein that regulates intracellular (e.g. signal transduction) and extracellular processes (e.g. immunity, leukocyte mobilization) that support cell survival. The protein is best known...
8.
Gallardo M, Malaney P, Aitken M, Zhang X, Link T, Shah V, et al.
J Natl Cancer Inst
. 2019 May;
112(1):95-106.
PMID: 31077320
Background: Heterogeneous nuclear ribonucleoprotein K (hnRNP K) is an RNA-binding protein that is aberrantly expressed in cancers. We and others have previously shown that reduced hnRNP K expression downmodulates tumor-suppressive...
9.
Wang G, Ma H, Wang J, Khan M
Toxicol Appl Pharmacol
. 2018 Oct;
362:28-34.
PMID: 30315841
Trichloroethene (TCE), a common environmental toxicant and widely used industrial solvent, has been implicated in the development of various autoimmune diseases (ADs). Although oxidative stress has been involved in TCE-mediated...
10.
Ruvolo P, Ma H, Ruvolo V, Zhang X, Mu H, Schober W, et al.
Haematologica
. 2017 Sep;
102(12):2048-2057.
PMID: 28912176
Nearly one-third of patients with acute myeloid leukemia have FMS-like tyrosine kinase 3 mutations and thus have poor survival prospects. Receptor tyrosine kinase anexelekto is critical for FMS-like tyrosine kinase...