Huang-Chun Lien
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Explore the profile of Huang-Chun Lien including associated specialties, affiliations and a list of published articles.
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Articles
59
Citations
1363
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0
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Recent Articles
1.
Lien H, Yu H, Yu W, Lin S, Chen T, Chen I, et al.
Breast Cancer Res
. 2024 Sep;
26(1):130.
PMID: 39256881
Background: Although tumor cells undergoing epithelial-mesenchymal transition (EMT) typically exhibit spindle morphology in experimental models, such histomorphological evidence of EMT has predominantly been observed in rare primary spindle carcinomas. The...
2.
Lien H, Lo C, Lee Y, Lin P, Wang M, Kuo W, et al.
Breast Cancer Res
. 2024 Jun;
26(1):100.
PMID: 38867307
Background: Immunohistochemistry (IHC) and in situ hybridization (ISH) remain standard biomarkers for therapeutic decisions in human epidermal growth factor 2 (HER2)-positive breast cancers (BCs); however, they are insufficient to explain...
3.
Chang C, Hang J, Chen C, Tung C, Lien H, Lai C, et al.
J Chin Med Assoc
. 2023 Oct;
86(12):1053-1059.
PMID: 37793013
Background: Estrogen receptor (ER) testing performed using immunohistochemistry (IHC) is a critical predictive tool for breast cancer treatment. This study aimed to investigate the use of tonsil control for monitoring...
4.
Tseng Y, Li Y, Lee Y, Hu H, Zhang M, Hung T, et al.
Arch Pathol Lab Med
. 2023 Aug;
148(3):e48-e56.
PMID: 37639453
Context.—: RNA sequencing study has demonstrated that human epidermal growth factor receptor 2 (HER2) RNA levels influence anti-HER2 therapeutic efficacy. However, in situ HER2 RNA expression (isHRE), which evaluates HER2...
5.
Lien H, Hsu C, Lu Y, Chen T, Chen I, Li Y, et al.
Breast Cancer Res
. 2023 Jan;
25(1):11.
PMID: 36707876
Background: Metaplastic breast carcinoma (MpBC) typically consists of carcinoma of no special type (NST) with various metaplastic components. Although previous transcriptomic and proteomic studies have reported subtype-related heterogeneity, the intracase...
6.
Ma W, Chang D, Lin C, Liu K, Liang P, Lien H, et al.
Oncologist
. 2022 Oct;
27(12):1008-1015.
PMID: 36215276
Background: Pseudocirrhosis is an imaging finding of malignancies with liver metastasis with or without clinical liver cirrhosis-related portal hypertension (pHTN). This study defined evident pHTN by the presence of esophageal...
7.
Wang C, Lee Y, Khalil M, Lin K, Yu C, Lien H
Sci Rep
. 2022 Jul;
12(1):11623.
PMID: 35803996
Joint analysis of multiple protein expressions and tissue morphology patterns is important for disease diagnosis, treatment planning, and drug development, requiring cross-staining alignment of multiple immunohistochemical and histopathological slides. However,...
8.
Khalil M, Lee Y, Lien H, Jeng Y, Wang C
Diagnostics (Basel)
. 2022 Apr;
12(4).
PMID: 35454038
Breast cancer is the leading cause of death for women globally. In clinical practice, pathologists visually scan over enormous amounts of gigapixel microscopic tissue slide images, which is a tedious...
9.
El Bairi K, Haynes H, Blackley E, Fineberg S, Shear J, Turner S, et al.
NPJ Breast Cancer
. 2021 Dec;
7(1):150.
PMID: 34853355
The advent of immune-checkpoint inhibitors (ICI) in modern oncology has significantly improved survival in several cancer settings. A subgroup of women with breast cancer (BC) has immunogenic infiltration of lymphocytes...
10.
Tsai L, Lee Y, Lo C, Lien H, Wang M, Jan I, et al.
Surg Oncol
. 2021 Oct;
39:101667.
PMID: 34673474
Background: Current guidelines recommend harvesting ≥3 sentinel nodes if sentinel lymph node biopsy (SLNB) alone is considered after neoadjuvant therapy (NAT) for initially node-positive (cN+) breast cancer. We attempted to...