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Hsueh-Cheng Chiang

Explore the profile of Hsueh-Cheng Chiang including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 2001
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Recent Articles
1.
Wang C, Wu C, Lin C, Hsu M, Lin J, Huang C, et al.
Nat Commun . 2023 Nov; 14(1):7153. PMID: 37935667
Inaccessibility of stored memory in ensemble cells through the forgetting process causes animals to be unable to respond to natural recalling cues. While accumulating evidence has demonstrated that reactivating memory-stored...
2.
Wu M, Liao T, Wu C, Hsieh T, Kuo P, Li Y, et al.
Cell Rep . 2023 Oct; 42(10):113207. PMID: 37782557
Animals rapidly acquire surrounding information to perform the appropriate behavior. Although social learning is more efficient and accessible than self-learning for animals, the detailed regulatory mechanism of social learning remains...
3.
Hsieh T, Chiang H
Life Sci . 2023 Sep; 332:122118. PMID: 37741318
Aims: Evidence indicates accumulating Aβ peptides in brain activates immune responses in neuronal and peripheral system, which may collaboratively influence pathogenesis of Alzheimer's disease (AD). We aim to investigate whether...
4.
Hu Y, Hsu C, Tseng Y, Lin C, Chiang H, Chiang A, et al.
Biomed Opt Express . 2023 Jun; 14(6):2478-2491. PMID: 37342698
Temporal focusing multiphoton excitation microscopy (TFMPEM) enables fast widefield biotissue imaging with optical sectioning. However, under widefield illumination, the imaging performance is severely degraded by scattering effects, which induce signal...
5.
Cheng K, Cheung C, Chiang H
Aging Dis . 2022 Jun; 13(3):868-883. PMID: 35656119
Amyloid cascade hypothesis proposes that amyloid β (Aβ) accumulation is the initiator and major contributor to the development of Alzheimer's disease (AD). However, this hypothesis has recently been challenged by...
6.
Cheng K, Huang C, Hsieh T, Chiang H
IUBMB Life . 2022 May; 74(8):754-762. PMID: 35531745
Accumulated Aβ is one of the hallmarks of Alzheimer's disease. Although accumulated results from in vivo and in vitro studies have shown that accumulated Aβ causes learning and memory deficit,...
7.
Cheng K, Hwang Y, Chiang H
FASEB J . 2021 Dec; 36(1):e22072. PMID: 34907598
Alzheimer's disease (AD) is marked by cognitive impairment, massive cell death, and reduced life expectancy. Pathologically, accumulated beta-amyloid (Aβ) aggregates and hyperphosphorylated tau protein is the hallmark of the disease....
8.
Cheng K, Chen Y, Wu C, Lee W, Cheung C, Chiang H
Mol Neurobiol . 2021 Jul; 58(10):5224-5238. PMID: 34273104
Accumulated beta-amyloid (Aβ) in the brain is the hallmark of Alzheimer's disease (AD). Despite Aβ accumulation is known to trigger cellular dysfunctions and learning and memory damage, the detailed molecular...
9.
Lee W, Chiang M, Chang L, Lee J, Tsai Y, Chiu T, et al.
PLoS Genet . 2020 Aug; 16(8):e1008963. PMID: 32780743
Long-term memory (LTM) formation depends on the conversed cAMP response element-binding protein (CREB)-dependent gene transcription followed by de novo protein synthesis. Thirsty fruit flies can be trained to associate an...
10.
Shyu W, Lee W, Chiang M, Chang C, Fu T, Chiang H, et al.
PLoS Genet . 2019 May; 15(5):e1008153. PMID: 31071084
Electrical synapses between neurons, also known as gap junctions, are direct cell membrane channels between adjacent neurons. Gap junctions play a role in the synchronization of neuronal network activity; however,...