Howard W Clark
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Explore the profile of Howard W Clark including associated specialties, affiliations and a list of published articles.
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34
Citations
450
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Recent Articles
1.
Ahmed W, Veluthandath A, Madsen J, Clark H, Dushianthan A, Postle A, et al.
Talanta
. 2024 Apr;
275:126062.
PMID: 38615457
Neonatal respiratory distress syndrome (nRDS) is a challenging condition to diagnose which can lead to delays in receiving appropriate treatment. Mid infrared (IR) spectroscopy is capable of measuring the concentrations...
2.
Dushianthan A, Clark H, Brealey D, Pratt D, Fink J, Madsen J, et al.
Sci Rep
. 2023 Nov;
13(1):20946.
PMID: 38017061
SARS-CoV-2 directly targets alveolar epithelial cells and can lead to surfactant deficiency. Early reports suggested surfactant replacement may be effective in improving outcomes. The aim of the study to assess...
3.
Dargaville P, Kamlin C, Orsini F, Wang X, De Paoli A, Kanmaz Kutman H, et al.
JAMA
. 2023 Sep;
330(11):1054-1063.
PMID: 37695601
Importance: The long-term effects of surfactant administration via a thin catheter (minimally invasive surfactant therapy [MIST]) in preterm infants with respiratory distress syndrome remain to be definitively clarified. Objective: To...
4.
Hristova V, Watson A, Chaerkady R, Glover M, Ackland J, Angerman B, et al.
ERJ Open Res
. 2023 May;
9(3).
PMID: 37228288
Rationale: Pulmonary surfactant is vital for lung homeostasis as it reduces surface tension to prevent alveolar collapse and provides essential immune-regulatory and antipathogenic functions. Previous studies demonstrated dysregulation of some...
5.
Reid E, Kamlin O, Orsini F, De Paoli A, Clark H, Soll R, et al.
Clin Trials
. 2023 May;
20(5):479-485.
PMID: 37144610
Background: Blinding of treatment allocation from treating clinicians in neonatal randomised controlled trials can minimise performance bias, but its effectiveness is rarely assessed. Methods: To examine the effectiveness of blinding...
6.
Ahmed W, Veluthandath A, Rowe D, Madsen J, Clark H, Postle A, et al.
Sensors (Basel)
. 2022 Mar;
22(5).
PMID: 35270894
The authors of this study developed the use of attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) combined with machine learning as a point-of-care (POC) diagnostic platform, considering neonatal respiratory...
7.
Dargaville P, Kamlin C, Orsini F, Wang X, De Paoli A, Kanmaz Kutman H, et al.
JAMA
. 2021 Dec;
326(24):2478-2487.
PMID: 34902013
Importance: The benefits of surfactant administration via a thin catheter (minimally invasive surfactant therapy [MIST]) in preterm infants with respiratory distress syndrome are uncertain. Objective: To examine the effect of...
8.
Postle A, Clark H, Fink J, Madsen J, Koster G, Panchal M, et al.
Am J Respir Crit Care Med
. 2021 Dec;
205(4):471-473.
PMID: 34874818
No abstract available.
9.
Bhatt R, Clark H, Girardis M, Busani S
BMJ Open Respir Res
. 2021 Sep;
8(1).
PMID: 34521648
Acute respiratory distress syndrome (ARDS) related to SARS-CoV-2 infection has some unusual characteristics that differentiate it from the pathophysiology described in the more 'typical' ARDS. Among multiple hypotheses, a close...
10.
Ellis S, Hall E, Panchal M, Flinders B, Madsen J, Koster G, et al.
J Lipid Res
. 2021 Jan;
62:100023.
PMID: 33453219
Mass spectrometry imaging (MSI) visualizes molecular distributions throughout tissues but is blind to dynamic metabolic processes. Here, MSI with high mass resolution together with multiple stable isotope labeling provided spatial...