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Howard Sard

Explore the profile of Howard Sard including associated specialties, affiliations and a list of published articles. Areas
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Articles 2
Citations 41
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Recent Articles
1.
McKew J, Foley M, Thakker P, Behnke M, Lovering F, Sum F, et al.
J Med Chem . 2006 Jan; 49(1):135-58. PMID: 16392799
Compound 1 was previously reported to be a potent inhibitor of cPLA(2)alpha in both artificial monomeric substrate and cell-based assays. However, 1 was inactive in whole blood assays previously used...
2.
Sard H, Kumaran G, Morency C, Roth B, Toth B, He P, et al.
Bioorg Med Chem Lett . 2005 Aug; 15(20):4555-9. PMID: 16061378
An SAR study of psilocybin and psilocin derivatives reveals that 1-methylpsilocin is a selective agonist at the h5-HT(2C) receptor. The corresponding phosphate derivative, 1-methylpsilocybin, shows efficacy in an animal model...