Hovsep Mahdessian
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Explore the profile of Hovsep Mahdessian including associated specialties, affiliations and a list of published articles.
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11
Citations
238
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Recent Articles
1.
Blomstrom Lundqvist C, Sjalander S, Garcia Rodriguez L, Akerborg O, Jin G, Caleyachetty A, et al.
J Med Econ
. 2022 Aug;
25(1):1085-1091.
PMID: 35997241
Aims: A third of non-valvular atrial fibrillation (NVAF) patients are non-adherent to direct oral anticoagulants (DOACs). Estimates of the economic value of full adherence and the cost of two types...
2.
Liu W, Mahdessian H, Helgadottir H, Zhou X, Thutkawkorapin J, Jiao X, et al.
Mol Carcinog
. 2021 Nov;
61(3):288-300.
PMID: 34758156
To search for colorectal cancer (CRC) risk loci, Swedish samples were used for a genome-wide haplotype analysis. A logistic regression model was employed in 2663 CRC cases and 1642 controls...
3.
Taxiarchis A, Mahdessian H, Silveira A, Fisher R, Vant Hooft F
J Lipid Res
. 2019 Mar;
60(6):1069-1077.
PMID: 30918066
Patatin-like phospholipase domain-containing proteins (PNPLAs) are involved in triglyceride hydrolysis and lipid-droplet homeostasis in mice, but the physiological significance of the PNPLAs for triglyceride metabolism in human hepatocytes is unclear....
4.
Recurrent, low-frequency coding variants contributing to colorectal cancer in the Swedish population
Jiao X, Liu W, Mahdessian H, Bryant P, Ringdahl J, Timofeeva M, et al.
PLoS One
. 2018 Mar;
13(3):e0193547.
PMID: 29547645
Genome-wide association studies (GWAS) have identified dozens of common genetic variants associated with risk of colorectal cancer (CRC). However, the majority of CRC heritability remains unclear. In order to discover...
5.
Thutkawkorapin J, Mahdessian H, Barber T, Picelli S, von Holst S, Lundin J, et al.
Oncotarget
. 2018 Mar;
9(13):11170-11179.
PMID: 29541405
Highly penetrant cancer syndromes account for less than 5% of all cases with familial colorectal cancer (CRC), and other genetic contribution explains the majority of the genetic contribution to CRC....
6.
Liu W, Jiao X, Thutkawkorapin J, Mahdessian H, Lindblom A
Oncotarget
. 2018 Jan;
8(66):110300-110310.
PMID: 29299148
A germline mutation in cancer predisposing genes is known to increase the risk of more than one tumor type. In order to find loci associated with many types of cancer,...
7.
Mahdessian H, Taxiarchis A, Popov S, Silveira A, Franco-Cereceda A, Hamsten A, et al.
Proc Natl Acad Sci U S A
. 2014 Jun;
111(24):8913-8.
PMID: 24927523
Genome-wide association studies have identified a locus on chromosome 19 associated with plasma triglyceride (TG) concentration and nonalcoholic fatty liver disease. However, the identity and functional role of the gene(s)...
8.
Mannila M, Mahdessian H, Franco-Cereceda A, Eggertsen G, de Faire U, Syvanen A, et al.
Arterioscler Thromb Vasc Biol
. 2013 Feb;
33(5):1063-9.
PMID: 23430611
Objective: There is compelling evidence that the plasma apolipoprotein E (APOE) concentration, in addition to the APOE ε2/ε3/ε4 genotype, influences plasma lipoprotein levels, but the functional genetic variants influencing the...
9.
Chernogubova E, Strawbridge R, Mahdessian H, Malarstig A, Krapivner S, Gigante B, et al.
Arterioscler Thromb Vasc Biol
. 2012 Mar;
32(6):1526-34.
PMID: 22460556
Objective: Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a circulating protein that influences plasma low-density lipoprotein concentration and susceptibility to coronary heart disease. Circulating PCSK9 levels show considerable interindividual differences,...
10.
Stahl P, Bjursell M, Mahdessian H, Hober S, Jirstrom K, Lundeberg J
PLoS One
. 2011 Jun;
6(6):e20794.
PMID: 21698250
Biomarker identification is of utmost importance for the development of novel diagnostics and therapeutics. Here we make use of a translational database selection strategy, utilizing data from the Human Protein...