Houzao Chen
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Explore the profile of Houzao Chen including associated specialties, affiliations and a list of published articles.
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31
Citations
324
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Recent Articles
1.
Shi J, Pei X, Peng J, Wu C, Lv Y, Wang X, et al.
Clin Transl Med
. 2025 Feb;
15(2):e70226.
PMID: 39902678
Background: Anti-melanoma differentiation-associated gene 5-positive dermatomyositis (anti-MDA5+ DM) is a rare inflammatory autoimmune disorder often complicated by life-threatening rapidly progressive interstitial lung disease (RP-ILD). The underlying mechanisms driving immune dysfunction...
2.
Zhang L, Zhang M, Huang J, Huang J, Zhang Y, Zhang Y, et al.
Nat Cardiovasc Res
. 2024 Nov;
3(11):1318-1336.
PMID: 39528719
Mitochondrial dynamics and mitophagy are intimately linked physiological processes that are essential for cardiac homeostasis. Here we show that cardiac Krüppel-like factor 9 (Klf9) is dysregulated in human and rodent...
3.
Li H, Ma L, Zhu N, Liang X, Tian X, Liu K, et al.
Biomaterials
. 2024 Oct;
314:122882.
PMID: 39423513
Mesenchymal stromal cells (MSCs) are believed to migrate to injury sites, release chemical attractants, and either recruit local stem cells or modulate the immune system positively. Although MSCs are highly...
4.
Gong K, Xue C, Feng Z, Pan R, Wang M, Chen S, et al.
Nat Commun
. 2024 Sep;
15(1):7902.
PMID: 39256382
No abstract available.
5.
Xue C, Zeng P, Gong K, Li Q, Feng Z, Wang M, et al.
Cell Rep
. 2024 Sep;
43(9):114691.
PMID: 39235944
The strategy of lowering cholesterol levels by promoting cholesterol excretion is still lacking, and few molecular targets act on multiple cholesterol metabolic processes. In this study, we find that Nogo-B...
6.
Gong K, Xue C, Feng Z, Pan R, Wang M, Chen S, et al.
Nat Commun
. 2024 Aug;
15(1):6845.
PMID: 39122737
Glucagon-like peptide 1 (GLP1), which is mainly processed and cleaved from proglucagon in enteroendocrine cells (EECs) of the intestinal tract, acts on the GLP1 receptor in pancreatic cells to stimulate...
7.
Zhang P, Hu X, Li Z, Liu Q, Liu L, Jin Y, et al.
Sci Immunol
. 2024 Jun;
9(96):eadj5465.
PMID: 38875319
Nucleic acids are major structures detected by the innate immune system. Although intracellular single-stranded DNA (ssDNA) accumulates during pathogen infection or disease, it remains unclear whether and how intracellular ssDNA...
8.
Wei Z, Yang B, Wang H, Lv S, Chen H, Liu D
Chin Med J (Engl)
. 2024 Mar;
137(8):921-935.
PMID: 38527930
Caloric restriction (CR) is a well-established dietary intervention known to extend healthy lifespan and exert positive effects on aging-related diseases, including cardiovascular conditions. Sirtuins, a family of nicotinamide adenine dinucleotide...
9.
Jiang H, Bai L, Song S, Yin Q, Shi A, Zhou B, et al.
Life Sci Alliance
. 2023 Apr;
6(6).
PMID: 37037595
Enhancer of zeste homolog 2 (EZH2) is an important transcriptional regulator in development that catalyzes H3K27me3. The role of EZH2 in epicardial development is still unknown. In this study, we...
10.
Huang C, Ding T, Zhang Y, Li X, Sun X, Lv S, et al.
J Mol Cell Cardiol
. 2023 Feb;
177:21-27.
PMID: 36827872
The longevity protein p66 is essential for the senescence signaling that is involved in heart regeneration and remodeling. However, the exact role of p66 in heart regeneration is unknown. In...