Hossein Batebi
Overview
Explore the profile of Hossein Batebi including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
88
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Recent Articles
1.
Batebi H, Perez-Hernandez G, Rahman S, Lan B, Kamprad A, Shi M, et al.
Nat Struct Mol Biol
. 2024 Jun;
31(11):1692-1701.
PMID: 38867113
G-protein-coupled receptors (GPCRs) activate heterotrimeric G proteins by promoting guanine nucleotide exchange. Here, we investigate the coupling of G proteins with GPCRs and describe the events that ultimately lead to...
2.
Papasergi-Scott M, Perez-Hernandez G, Batebi H, Gao Y, Eskici G, Seven A, et al.
Nature
. 2024 Mar;
629(8014):1182-1191.
PMID: 38480881
G-protein-coupled receptors (GPCRs) activate heterotrimeric G proteins by stimulating guanine nucleotide exchange in the Gα subunit. To visualize this mechanism, we developed a time-resolved cryo-EM approach that examines the progression...
3.
Papasergi-Scott M, Perez-Hernandez G, Batebi H, Gao Y, Eskici G, Seven A, et al.
bioRxiv
. 2023 Mar;
PMID: 36993214
G protein-coupled receptors (GPCRs) activate heterotrimeric G proteins by stimulating the exchange of guanine nucleotide in the Gα subunit. To visualize this mechanism, we developed a time-resolved cryo-EM approach that...
4.
Beliu G, Altrichter S, Guixa-Gonzalez R, Hemberger M, Brauer I, Dahse A, et al.
Mol Cell
. 2021 Jan;
81(5):905-921.e5.
PMID: 33497605
Adhesion G protein-coupled receptors (aGPCRs)/family B2 GPCRs execute critical tasks during development and the operation of organs, and their genetic lesions are associated with human disorders, including cancers. Exceptional structural...
5.
Ma X, Hu Y, Batebi H, Heng J, Xu J, Liu X, et al.
Proc Natl Acad Sci U S A
. 2020 Sep;
117(37):23096-23105.
PMID: 32868434
The β-adrenergic receptor (βAR) is a prototypical G protein-coupled receptor (GPCR) that preferentially couples to the stimulatory G protein G and stimulates cAMP formation. Functional studies have shown that the...
6.
Batebi H, Dragelj J, Imhof P
Proteins
. 2018 Jan;
86(4):439-453.
PMID: 29344998
Apurinic/apyrimidinic endonuclease 1 (Ape1) is an important metal-dependent enzyme in the base excision repair mechanism, responsible for the backbone cleavage of abasic DNA through a phosphate hydrolysis reaction. Molecular dynamics...