Hongju Deng
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Explore the profile of Hongju Deng including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
321
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Recent Articles
1.
Wang C, Guo J, Liu Q, Zeng X, Liu Y, Deng Y, et al.
Int J Biol Macromol
. 2024 Feb;
262(Pt 2):130084.
PMID: 38350584
Accidental bleeding is an unavoidable problem in daily life. To avoid the risk of excessive blood loss, it is urgent to design a functional material that can quickly stop bleeding....
2.
Ingle H, Makimaa H, Aggarwal S, Deng H, Foster L, Li Y, et al.
Sci Adv
. 2023 Sep;
9(37):eadi2562.
PMID: 37703370
Norovirus is a leading cause of epidemic viral gastroenteritis, with no currently approved vaccines or antivirals. Murine norovirus (MNoV) is a well-characterized model of norovirus pathogenesis in vivo, and persistent...
3.
Lee S, Kalugotla G, Ingle H, Rodgers R, Wu C, Wang Y, et al.
Autophagy
. 2021 Sep;
18(5):1062-1077.
PMID: 34520306
Mutations in the macroautophagy/autophagy gene are responsible for Vici syndrome, a human genetic disease characterized by combined immunodeficiency. Previously, we found that mice exhibit hyperinflammation in the lungs mediated by...
4.
Su X, Floyd D, Hughes A, Xiang J, Schneider J, Uluckan O, et al.
J Clin Invest
. 2012 Sep;
122(10):3579-92.
PMID: 22996695
The adenosine diphosphate (ADP) receptor P2RY12 (purinergic receptor P2Y, G protein coupled, 12) plays a critical role in platelet aggregation, and P2RY12 inhibitors are used clinically to prevent cardiac and...
5.
Nyalala J, Brown A, Luo S, Deng H, Moursi M
Vasc Endovascular Surg
. 2012 Jan;
45(8):720-6.
PMID: 22262116
Background: To investigate whether estrogen may attenuate neointima formation in hyperhomocysteinemic rat carotid endarterectomy. Methods: Rats were divided into 6 groups: ovariectomized estradiol-treated homocysteine or chow; ovariectomized placebo-treated homocysteine or...
6.
Heller E, Hurchla M, Xiang J, Su X, Chen S, Schneider J, et al.
Cancer Res
. 2011 Dec;
72(4):897-907.
PMID: 22186138
Hedgehog (Hh) signaling is implicated in bone development and cellular transformation. Here we show that inhibition of Hh pathway activity inhibits tumor growth through effects on the microenvironment. Pharmacologic inhibition...
7.
Rauch D, Hurchla M, Harding J, Deng H, Shea L, Eagleton M, et al.
PLoS One
. 2011 Jan;
5(12):e15755.
PMID: 21209895
The ARF tumor suppressor regulates p53 as well as basic developmental processes independent of p53, including osteoclast activation, by controlling ribosomal biogenesis. Here we provide evidence that ARF is a...
8.
Morgan E, Schneider J, Baroni T, Uluckan O, Heller E, Hurchla M, et al.
FASEB J
. 2009 Nov;
24(4):1117-27.
PMID: 19933310
The purpose of this work was to determine platelet and myeloid cell-specific requirements for beta3-containing integrins in hemostasis, bone resorption, and tumor growth. LoxP-flanked mice were generated to study the...
9.
Wadas T, Deng H, Sprague J, Zheleznyak A, Weilbaecher K, Anderson C
J Nucl Med
. 2009 Oct;
50(11):1873-80.
PMID: 19875645
Unlabelled: This article describes the evaluation of the radiopharmaceutical (64)Cu-CB-TE2A-c(RGDyK) ((64)Cu-RGD) as an imaging agent for osteolytic bone metastases and their associated inflammation by targeting of the alpha(v)beta(3) integrin on...
10.
The bisphosphonate zoledronic acid decreases tumor growth in bone in mice with defective osteoclasts
Hirbe A, Roelofs A, Floyd D, Deng H, Becker S, Lanigan L, et al.
Bone
. 2009 May;
44(5):908-16.
PMID: 19442620
Bisphosphonates (BPs), bone targeted drugs that disrupt osteoclast function, are routinely used to treat complications of bone metastasis. Studies in preclinical models of cancer have shown that BPs reduce skeletal...