Hong Kiat Ng
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Explore the profile of Hong Kiat Ng including associated specialties, affiliations and a list of published articles.
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18
Citations
1302
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Recent Articles
1.
Tan K, Tay D, Tan W, Ng H, Wong E, Morley M, et al.
Clin Epigenetics
. 2025 Mar;
17(1):45.
PMID: 40057770
Background: Methylation changes linked to dilated cardiomyopathy (DCM) affect cardiac gene expression. We investigate DCM mechanisms regulated by CpG methylation using multi-omics and causal analyses in the largest cohort of...
2.
Jain P, Ng H, Tay D, Mina T, Low D, Sadhu N, et al.
medRxiv
. 2025 Feb;
PMID: 39990582
To identify biomarkers and pathways to Type-2 diabetes (T2D), a major global disease, we completed array-based epigenome-wide association in whole blood in 5,709 Asian people. We found 323 Sentinel CpGs...
3.
Smith H, Ng H, Moodie J, Gadd D, McCartney D, Bernabeu E, et al.
Am J Hum Genet
. 2024 Dec;
112(1):106-115.
PMID: 39706196
Exploring the molecular correlates of metabolic health measures may identify their shared and unique biological processes and pathways. Molecular proxies of these traits may also provide a more objective approach...
4.
Mina T, Xie W, Low D, Wang X, Lam B, Sadhu N, et al.
Lancet Diabetes Endocrinol
. 2024 Sep;
12(10):704-715.
PMID: 39217997
Background: Type 2 diabetes, cardiovascular disease, and related cardiometabolic disturbances are increasing rapidly in the Asia-Pacific region. We investigated the contribution of excess adiposity, a key determinant of type 2...
5.
Smith H, Ng H, Moodie J, Gadd D, McCartney D, Bernabeu E, et al.
medRxiv
. 2024 Jun;
PMID: 38853823
Exploring the molecular correlates of metabolic health measures may identify the shared and unique biological processes and pathways that they track. Here, we performed epigenome-wide association studies (EWASs) of six...
6.
Hillary R, Ng H, McCartney D, Elliott H, Walker R, Campbell A, et al.
Cell Genom
. 2024 May;
4(5):100544.
PMID: 38692281
Chronic inflammation is a hallmark of age-related disease states. The effectiveness of inflammatory proteins including C-reactive protein (CRP) in assessing long-term inflammation is hindered by their phasic nature. DNA methylation...
7.
Yew Y, Mina T, Ng H, Lam B, Riboli E, Lee E, et al.
Int J Obes (Lond)
. 2023 Jul;
47(10):963-969.
PMID: 37479793
Background: Skin diseases impact significantly on the quality of life and psychology of patients. Obesity has been observed as a risk factor for skin diseases. Skin epidermal barrier dysfunctions are...
8.
Mina T, Yew Y, Ng H, Sadhu N, Wansaicheong G, Dalan R, et al.
Lancet Reg Health West Pac
. 2023 Feb;
33:100710.
PMID: 36851942
Background: Obesity and related metabolic disturbances including diabetes, hypertension and hyperlipidemia predict future cognitive decline. Asia has a high prevalence of both obesity and metabolic disease, potentially amplifying the future...
9.
Loh M, Zhang W, Ng H, Schmid K, Lamri A, Tong L, et al.
Commun Biol
. 2022 May;
5(1):441.
PMID: 35513483
No abstract available.
10.
Identification of genetic effects underlying type 2 diabetes in South Asian and European populations
Loh M, Zhang W, Ng H, Schmid K, Lamri A, Tong L, et al.
Commun Biol
. 2022 Apr;
5(1):329.
PMID: 35393509
South Asians are at high risk of developing type 2 diabetes (T2D). We carried out a genome-wide association meta-analysis with South Asian T2D cases (n = 16,677) and controls (n ...