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Hong-Yan Gu

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Articles 26
Citations 633
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Recent Articles
1.
Xu J, Zheng H, Lu H, Wang L, Wu B, Lv X, et al.
Lancet Respir Med . 2025 Jan; 13(2):166-176. PMID: 39805296
Background: Bronchiectasis is a disease with a global impact, but most published data come from high-income countries. We aimed to describe the clinical characteristics of patients with bronchiectasis in China....
2.
Gao Y, Lu H, Zheng H, Cao C, Chu D, Fan H, et al.
ERJ Open Res . 2024 Feb; 10(1). PMID: 38410702
Chronic (PA) infection significantly contributes to morbidity and mortality in bronchiectasis patients. Initiating antibiotics early may lead to the eradication of PA. Here we outline the design of a trial...
3.
Gao Y, Lu H, Mao B, Guan W, Song Y, Li Y, et al.
Respir Res . 2022 Dec; 23(1):328. PMID: 36463140
Background: Bronchiectasis is a highly heterogeneous chronic airway disease with marked geographic and ethnic variations. Most influential cohort studies to date have been performed in Europe and USA, which serve...
4.
Tao X, Liu P, Gu H, Lian D, Gao L, Tao W, et al.
Drug Des Devel Ther . 2020 Aug; 14:2809-2817. PMID: 32764880
Introduction: Osteoarthritis is the most prevalent articular disease in the elderly. We aimed to explore the role of cordycepin (COR) in the progression and development of osteoarthritis and its correlation...
5.
Shi Z, Liu Y, Gu H, Xu X, Yan C, Yang X, et al.
Biopharm Drug Dispos . 2020 Feb; 41(3):101-110. PMID: 32017134
Methotrexate (MTX) pharmacokinetics has substantial inter-individual variability and toxicity. In children with medulloblastoma treated with high-dose methotrexate (HD-MTX), the pharmacokinetic properties of methotrexate have not been established. A total of...
6.
Yang J, Liu J, Gu H, Lv W, Zhao H, Li G
Zhongguo Zhen Jiu . 2014 Oct; 34(8):833-6. PMID: 25335274
The clinical efficacy of acupuncture and moxibustion for post-stroke constipation was systematically reviewed. By computerized and manual retrieval of clinical research literature regarding acupuncture and moxibustion for post-stroke constipation, the...
7.
Wang J, Zhao Q, Qi Q, Gu H, Rong J, Mu R, et al.
J Cell Biochem . 2011 Jan; 112(2):509-19. PMID: 21268072
As an oncoprotein, mutant p53 is a potential tumor-specific target for cancer therapy. Most mutated forms of the protein are largely accumulated in cancer cells due to their increased stability....
8.
Rong J, Hu R, Qi Q, Gu H, Zhao Q, Wang J, et al.
Cancer Lett . 2009 May; 284(1):102-12. PMID: 19428175
Gambogic acid (GA), the natural compound extracted from gamboges, has recently been established as a potent anti-tumor agent. Although it was proved that GA enhances p53 protein level through inhibition...
9.
Wang J, Zhao X, Qi Q, Tao L, Zhao Q, Mu R, et al.
Food Chem Toxicol . 2009 May; 47(7):1716-21. PMID: 19406196
Macranthoside B (MB) is a hederagenin saponin extracted from the flower bud of Lonicera macranthoides. In this study, we defined the anticancer effect of MB both in vitro and in...
10.
Yang Y, Hu Y, Gu H, Lu N, Liu W, Qi Q, et al.
J Pharm Pharmacol . 2008 Oct; 60(11):1459-63. PMID: 18957166
We reported previously that oroxylin A, a natural product isolated from Scutellariae Radix, was a potent apoptosis inducer of human hepatoma HepG2 cells. In this study, cell-cycle arrest of BGC-823...