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Holly Heimsath

Explore the profile of Holly Heimsath including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 188
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Recent Articles
1.
Jiang D, Goswami R, Dennis M, Heimsath H, Kozlowski P, Ardeshir A, et al.
Front Immunol . 2023 Dec; 14:1283343. PMID: 38124733
Introduction: It is becoming clearer that the microbiota helps drive responses to vaccines; however, little is known about the underlying mechanism. In this study, we aimed to identify microbial features...
2.
Berendam S, Morgan-Asiedu P, Mangan R, Li S, Heimsath H, Luo K, et al.
PLoS One . 2021 Dec; 16(12):e0256885. PMID: 34972105
Different HIV vaccine regimens elicit distinct plasma antibody responses in both human and nonhuman primate models. Previous studies in human and non-human primate infants showed that adjuvants influenced the quality...
3.
Martinez D, Tu J, Kumar A, Mangold J, Mangan R, Goswami R, et al.
mBio . 2020 Mar; 11(2). PMID: 32156815
Each year, >180,000 infants become infected via mother-to-child transmission (MTCT) of HIV despite the availability of effective maternal antiretroviral treatments, underlining the need for a maternal HIV vaccine. We characterized...
4.
Van Rompay K, Keesler R, Ardeshir A, Watanabe J, Usachenko J, Singapuri A, et al.
Sci Transl Med . 2019 Dec; 11(523). PMID: 31852797
Zika virus (ZIKV) infection of pregnant women is associated with congenital Zika syndrome (CZS) and no vaccine is available, although several are being tested in clinical trials. We tested the...
5.
Breitbach M, Newman C, Dudley D, Stewart L, Aliota M, Koenig M, et al.
PLoS Pathog . 2019 Aug; 15(8):e1007766. PMID: 31369649
Zika virus (ZIKV) and dengue virus (DENV) are genetically and antigenically related flaviviruses that now co-circulate in much of the tropical and subtropical world. The rapid emergence of ZIKV in...
6.
Himes J, Goswami R, Mangan R, Kumar A, Jeffries Jr T, Eudailey J, et al.
Mucosal Immunol . 2018 Aug; 11(6):1716-1726. PMID: 30115994
Breast milk HIV-1 transmission is currently the predominant contributor to pediatric HIV infections. Yet, only ~10% of breastfeeding infants born to untreated HIV-infected mothers become infected. This study assessed the...
7.
Coffey L, Keesler R, Pesavento P, Woolard K, Singapuri A, Watanabe J, et al.
Nat Commun . 2018 Jun; 9(1):2414. PMID: 29925843
Zika virus (ZIKV) infection of pregnant women can cause fetal microcephaly and other neurologic defects. We describe the development of a non-human primate model to better understand fetal pathogenesis. To...
8.
Premkumar L, Collins M, Graham S, Liou G, Lopez C, Jadi R, et al.
J Clin Microbiol . 2017 Dec; 56(3). PMID: 29263206
Zika virus (ZIKV) is an emerging flavivirus that can cause birth defects and neurologic complications. Molecular tests are effective for diagnosing acute ZIKV infection, although the majority of infections produce...
9.
Fan Q, Nelson C, Bialas K, Chiuppesi F, Amos J, Gurley T, et al.
Clin Vaccine Immunol . 2017 Mar; 24(5). PMID: 28298291
Human cytomegalovirus (HCMV) is the most common congenital infection worldwide and the leading infectious cause of neurologic deficits and hearing loss in newborns. Development of a maternal HCMV vaccine to...