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Holly Colognato

Explore the profile of Holly Colognato including associated specialties, affiliations and a list of published articles. Areas
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Articles 34
Citations 1217
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Recent Articles
1.
Gorter R, Arreguin A, Oost W, de Jonge J, Kampinga H, Amor S, et al.
Glia . 2025 Mar; PMID: 40059514
In multiple sclerosis (MS), an influx of immune cells into the central nervous system leads to focal demyelinating lesions in the brain, optic nerve, and spinal cord. As MS progresses,...
2.
Arreguin A, Shao Z, Colognato H
Dis Model Mech . 2024 May; 17(4). PMID: 38721692
Duchenne muscular dystrophy (DMD) is caused by mutations in the DMD gene, resulting in the loss of dystrophin, a large cytosolic protein that links the cytoskeleton to extracellular matrix receptors...
3.
Narine M, Azmi M, Umali M, Volz A, Colognato H
Front Cell Neurosci . 2023 Oct; 17:1254303. PMID: 37904733
Multiple Sclerosis (MS) is a chronic disease characterized by immune-mediated destruction of myelinating oligodendroglia in the central nervous system. Loss of myelin leads to neurological dysfunction and, if myelin repair...
4.
Narine M, Colognato H
Front Cell Neurosci . 2022 May; 16:892968. PMID: 35573837
Once believed to be part of the or "nerve glue" network in the central nervous system (CNS), oligodendroglial cells now have established roles in key neurological functions such as myelination,...
5.
Gorter R, Dijksman N, Baron W, Colognato H
Methods Cell Biol . 2022 Apr; 168:103-123. PMID: 35366978
Healthy myelin is essential for proper brain function. When the myelin sheath is damaged, fast saltatory impulse conduction is lost and neuronal axons become vulnerable to degeneration. Thus, regeneration of...
6.
Arreguin A, Colognato H
Front Mol Neurosci . 2020 Aug; 13:118. PMID: 32792907
Laminin α2 gene (LAMA2)-related Congenital Muscular Dystrophy (CMD) was distinguished by a defining central nervous system (CNS) abnormality-aberrant white matter signals by MRI-when first described in the 1990s. In the...
7.
Colognato H, Nishiyama A
Neurosci Lett . 2020 May; 730:134957. PMID: 32371158
No abstract available.
8.
Tomlinson L, Huang P, Colognato H
Dev Neurobiol . 2018 Mar; 78(7):687-700. PMID: 29569358
Aerobic exercise is known to influence brain function, e.g., enhancing executive function in both children and adults, with many of these influences being attributed to alterations in neurogenesis and neuronal...
9.
Shan X, Tomlinson L, Yang Q, Colognato H
Stem Cell Reports . 2018 Mar; 10(3):984-999. PMID: 29503085
The regulatory mechanisms that control neural stem cell (NSC) activation in the adult ventricular-subventricular zone (V-SVZ) stem cell niche have been the focus of intense investigation, yet how the niche...
10.
Siller S, Sharma H, Li S, Yang J, Zhang Y, Holtzman M, et al.
PLoS Genet . 2017 Dec; 13(12):e1007128. PMID: 29244804
Multiciliated cells of the airways, brain ventricles, and female reproductive tract provide the motive force for mucociliary clearance, cerebrospinal fluid circulation, and ovum transport. Despite their clear importance to human...