Holger Lorenz
Overview
Explore the profile of Holger Lorenz including associated specialties, affiliations and a list of published articles.
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Articles
25
Citations
910
Followers
0
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Recent Articles
1.
Benesova K, Kraus F, Carvalho R, Lorenz H, Horth C, Gunther J, et al.
Ann Rheum Dis
. 2022 Aug;
81(12):1730-1741.
PMID: 35922125
Objectives: Rheumatic immune-related adverse events (irAE) such as (poly)arthritis in patients undergoing immune checkpoint inhibitor (ICI) treatment pose a major clinical challenge. ICI therapy improves CD8 T cell (CD8) function,...
2.
Jaiswal A, Hoerth C, Zuniga Pereira A, Lorenz H
Sci Rep
. 2019 Sep;
9(1):12911.
PMID: 31501484
Induced morphology changes of cells and organelles are by far the easiest way to determine precise protein sub-locations and organelle quantities in light microscopy. By using hypotonic solutions to swell...
3.
Avci D, Malchus N, Heidasch R, Lorenz H, Richter K, Nessling M, et al.
J Biol Chem
. 2018 Dec;
294(8):2786-2800.
PMID: 30578301
The endoplasmic reticulum (ER), as a multifunctional organelle, plays crucial roles in lipid biosynthesis and calcium homeostasis as well as the synthesis and folding of secretory and membrane proteins. Therefore,...
4.
Uddin B, Partscht P, Chen N, Neuner A, Weiss M, Hardt R, et al.
EMBO Rep
. 2018 Nov;
20(1).
PMID: 30467237
CDC14A codes for a conserved proline-directed phosphatase, and mutations in the gene are associated with autosomal-recessive severe to profound deafness, due to defective kinocilia. A role of CDC14A in cilia...
5.
Ccdc61 controls centrosomal localization of Cep170 and is required for spindle assembly and symmetry
Barenz F, Kschonsak Y, Meyer A, Jafarpour A, Lorenz H, Hoffmann I
Mol Biol Cell
. 2018 Oct;
29(26):3105-3118.
PMID: 30354798
Microtubule nucleation was uncovered as a key principle of spindle assembly. However, the mechanistic details about microtubule nucleation and the organization of spindle formation and symmetry are currently being revealed....
6.
Hoffmann A, Dege T, Kunze R, Ernst A, Lorenz H, Bohler L, et al.
Stroke
. 2018 May;
49(6):1479-1487.
PMID: 29760276
Background And Purpose: Detection and localization of the early phase of blood-brain barrier disruption (BBBD) in vivo during cerebral ischemia/reperfusion injury remain a major challenge but may be a relevant...
7.
Yonashiro R, Tahara E, Bengtson M, Khokhrina M, Lorenz H, Chen K, et al.
Elife
. 2016 Mar;
5:e11794.
PMID: 26943317
Ribosome stalling during translation can potentially be harmful, and is surveyed by a conserved quality control pathway that targets the associated mRNA and nascent polypeptide chain (NC). In this pathway,...
8.
Kaistha B, Lorenz H, Schmidt H, Sipos B, Pawlak M, Gierke B, et al.
Cancer Res
. 2015 Dec;
76(1):96-107.
PMID: 26669866
Pancreatic ductal adenocarcinoma (PDAC) carries the most dismal prognosis of all solid tumors and is generally strongly resistant to currently available chemo- and/or radiotherapy regimens, including targeted molecular therapies. Therefore,...
9.
Stockklausner C, Raffel S, Klermund J, Bandapalli O, Beier F, Brummendorf T, et al.
Aging (Albany NY)
. 2015 Nov;
7(11):911-27.
PMID: 26546739
The TERT gene encodes for the reverse transcriptase activity of the telomerase complex and mutations in TERT can lead to dysfunctional telomerase activity resulting in diseases such as dyskeratosis congenita...
10.
Hernan Sendra G, Hoerth C, Wunder C, Lorenz H
Sci Rep
. 2015 Sep;
5:14160.
PMID: 26389818
No abstract available.