Holger Klein
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Explore the profile of Holger Klein including associated specialties, affiliations and a list of published articles.
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Articles
43
Citations
486
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Recent Articles
31.
Roepcke S, Stahlberg S, Klein H, Schulz M, Theobald L, Gohlke S, et al.
BMC Genomics
. 2011 Dec;
12:624.
PMID: 22185324
Background: Bioinformatic analyses of expression control sequences in promoters of co-expressed or functionally related genes enable the discovery of common regulatory sequence motifs that might be involved in co-ordinated gene...
32.
Klein H
Acta Crystallogr A
. 2011 Apr;
67(Pt 3):303-9.
PMID: 21487190
The structure solutions of the two phases Mn(2)O(3) and PbMnO(2.75) by precession electron diffraction (PED) are presented. In the powder samples used these structures could not be solved by X-ray...
33.
Klein H, David J
Acta Crystallogr A
. 2011 Apr;
67(Pt 3):297-302.
PMID: 21487189
Four crystal structures are solved from precession electron diffraction data using either the highest-quality experimental data available or voluntarily deteriorated data. The data quality was lowered by changing the intensity...
34.
Hallen L, Klein H, Stoschek C, Wehrmeyer S, Nonhoff U, Ralser M, et al.
Hum Mol Genet
. 2010 Oct;
20(1):104-14.
PMID: 20926453
Gene transcription is controlled by transcriptional regulators acting with specific co-regulators to allow gene activation and repression. Here, we report the identification of the KRAB-containing zinc-finger transcriptional regulator, ZBRK1, as...
35.
Kielbasa S, Klein H, Roider H, Vingron M, Bluthgen N
Nucleic Acids Res
. 2010 Jun;
38(Web Server issue):W275-80.
PMID: 20511592
The analysis of putative transcription factor binding sites in promoter regions of coregulated genes allows to infer the transcription factors that underlie observed changes in gene expression. While such analyses...
36.
Gemmi M, Klein H, Rageau A, Strobel P, Le Cras F
Acta Crystallogr B
. 2010 Jan;
66(Pt 1):60-8.
PMID: 20101084
A sample having stoichiometry Li[Ti(1.5)Ni(0.5)]O(4) has been synthesized to obtain a spinel structure. The resulting crystalline powder revealed a multiphase nature with spinel as the minor phase. The main phase...
37.
Driller K, Klein H, Jackstell R, Beller M
Angew Chem Int Ed Engl
. 2009 Jul;
48(33):6041-4.
PMID: 19591180
No abstract available.
38.
Pape U, Klein H, Vingron M
Bioinformatics
. 2009 Mar;
25(16):2103-9.
PMID: 19286833
Motivation: Statistical assessment of cis-regulatory modules (CRMs) is a crucial task in computational biology. Usually, one concludes from exceptional co-occurrences of DNA motifs that the corresponding transcription factors (TFs) are...
39.
Klein H, Vingron M
Genome Inform
. 2008 Jun;
18:109-18.
PMID: 18546479
Transcription factors (TFs) bind to the regulatory regions of genes in a cooperative manner. This article describes a method to detect pairs of transcription factor binding sites which co-occur in...
40.
Ahmed M, Buch C, Routaboul L, Jackstell R, Klein H, Spannenberg A, et al.
Chemistry
. 2006 Nov;
13(5):1594-601.
PMID: 17091522
Starting from [{Rh(cod)Cl}(2)] and 1,3-dimesitylimidazole-2-ylidenes the novel [RhCl(cod)(carbene)] complexes 1-5 have been synthesized, characterized, and tested in the hydroaminomethylation of aromatic olefins. The influence of different ligands and reaction parameters...