Heike Neubauer
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Explore the profile of Heike Neubauer including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
385
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Recent Articles
1.
Mitrovic S, Demalgiriya-Gamage C, Winter L, Kiechle T, Ebenhoch R, Neubauer H, et al.
Commun Biol
. 2024 Nov;
7(1):1588.
PMID: 39609618
GOLD domain seven-transmembrane helix (GOST) proteins form a new protein family involved in trafficking of membrane-associated cargo. They share a characteristic extracellular/luminal Golgi-dynamics (GOLD) domain, possibly responsible for ligand recognition....
2.
Thomas L, Martel E, Rist W, Uphues I, Hamprecht D, Neubauer H, et al.
Diabetes Obes Metab
. 2024 Apr;
26(6):2368-2378.
PMID: 38560764
Aim: To describe the biomarker strategy that was applied to select survodutide (BI 456906), BI 456908 and BI 456897 from 19 dual glucagon receptor (GCGR)/ glucagon-like peptide-1 receptor (GLP-1R) agonists...
3.
Bahrami E, Geiger T, Steixner-Kumar A, Santacruz D, Viollet C, Dick A, et al.
STAR Protoc
. 2023 Sep;
4(4):102597.
PMID: 37740914
Immune dysregulation and inflammation by hepatic-resident leukocytes is considered a key step in disease progression of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis toward cirrhosis and hepatocellular carcinoma. Here, we...
4.
Efthymiou V, Ding L, Balaz M, Sun W, Balazova L, Straub L, et al.
Nat Commun
. 2023 Jul;
14(1):4162.
PMID: 37443109
The current obesity epidemic and high prevalence of metabolic diseases necessitate efficacious and safe treatments. Brown adipose tissue in this context is a promising target with the potential to increase...
5.
Moser C, Gossele K, Balaz M, Balazova L, Horvath C, Kunzle P, et al.
Peptides
. 2023 Jun;
167:171047.
PMID: 37328068
The number of diabetic patients is rising globally and concomitantly so do the diabetes associated complications. The gut secretes a variety of proteins to control blood glucose levels and/or food...
6.
Schnapp G, Neubauer H, Buttner F, Handschuh S, Lingard I, Heilker R, et al.
Commun Chem
. 2023 Jan;
3(1):75.
PMID: 36703453
The C-type lectin family member lectin-like oxidized LDL receptor-1 (LOX-1) has been object of intensive research. Its modulation may offer a broad spectrum of therapeutic interventions ranging from cardiovascular diseases...
7.
Zimmermann T, Thomas L, Baader-Pagler T, Haebel P, Simon E, Reindl W, et al.
Mol Metab
. 2022 Nov;
66:101633.
PMID: 36356832
Objective: Obesity and its associated comorbidities represent a global health challenge with a need for well-tolerated, effective, and mechanistically diverse pharmaceutical interventions. Oxyntomodulin is a gut peptide that activates the...
8.
Markert E, Klein H, Viollet C, Rust W, Strobel B, Kauschke S, et al.
Front Cell Dev Biol
. 2022 Sep;
10:910040.
PMID: 36092714
The therapeutic potential of pluripotent stem cells is great as they promise to usher in a new era of medicine where cells or organs may be prescribed to replace dysfunctional...
9.
Dong H, Sun W, Shen Y, Balaz M, Balazova L, Ding L, et al.
Nat Metab
. 2022 Jan;
4(1):90-105.
PMID: 35027768
Healthy adipose tissue remodeling depends on the balance between de novo adipogenesis from adipogenic progenitor cells and the hypertrophy of adipocytes. De novo adipogenesis has been shown to promote healthy...
10.
Balazova L, Balaz M, Horvath C, Horvath A, Moser C, Kovanicova Z, et al.
Nat Commun
. 2021 Dec;
12(1):7144.
PMID: 34880217
Activation of thermogenic brown and beige adipocytes is considered as a strategy to improve metabolic control. Here, we identify GPR180 as a receptor regulating brown and beige adipocyte function and...