Holger H Hoos
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Explore the profile of Holger H Hoos including associated specialties, affiliations and a list of published articles.
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Articles
25
Citations
802
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0
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Recent Articles
1.
Schlender T, Viljanen M, van Rijn J, Mohr F, Peijnenburg W, Hoos H, et al.
Environ Sci Technol
. 2023 Jun;
57(46):17818-17830.
PMID: 37315216
Toxicological information as needed for risk assessments of chemical compounds is often sparse. Unfortunately, gathering new toxicological information experimentally often involves animal testing. Simulated alternatives, e.g., quantitative structure-activity relationship (QSAR)...
2.
Burggraaff L, Lenselink E, Jespers W, van Engelen J, Bongers B, Gorostiola Gonzalez M, et al.
J Chem Inf Model
. 2020 Apr;
60(9):4283-4295.
PMID: 32343143
Kinases are frequently studied in the context of anticancer drugs. Their involvement in cell responses, such as proliferation, differentiation, and apoptosis, makes them interesting subjects in multitarget drug design. In...
3.
Kerschke P, Hoos H, Neumann F, Trautmann H
Evol Comput
. 2018 Nov;
27(1):3-45.
PMID: 30475672
It has long been observed that for practically any computational problem that has been intensely studied, different instances are best solved using different algorithms. This is particularly pronounced for computationally...
4.
Blot A, Kessaci M, Jourdan L, Hoos H
Evol Comput
. 2018 Nov;
27(1):147-171.
PMID: 30407875
Automatic algorithm configuration (AAC) is becoming a key ingredient in the design of high-performance solvers for challenging optimisation problems. However, most existing work on AAC deals with configuration procedures that...
5.
Kerschke P, Kotthoff L, Bossek J, Hoos H, Trautmann H
Evol Comput
. 2017 Aug;
26(4):597-620.
PMID: 28836836
The Travelling Salesperson Problem (TSP) is one of the best-studied NP-hard problems. Over the years, many different solution approaches and solvers have been developed. For the first time, we directly...
6.
Majerowicz L, Shamir A, Sheffer A, Hoos H
IEEE Trans Vis Comput Graph
. 2015 Sep;
20(11):1507-18.
PMID: 26355330
Our homes and workspaces are filled with collections of dozens of artifacts laid out on surfaces such as shelves, counters, and mantles. The content and layout of these arrangements reflect...
7.
Aghaeepour N, Hoos H
BMC Bioinformatics
. 2013 Apr;
14:139.
PMID: 23617269
Background: Accurate structure prediction methods play an important role for the understanding of RNA function. Energy-based, pseudoknot-free secondary structure prediction is one of the most widely used and versatile approaches,...
8.
Aghaeepour N, Jalali A, ONeill K, Chattopadhyay P, Roederer M, Hoos H, et al.
Cytometry A
. 2012 Oct;
81(12):1022-30.
PMID: 23044634
Analysis of high-dimensional flow cytometry datasets can reveal novel cell populations with poorly understood biology. Following discovery, characterization of these populations in terms of the critical markers involved is an...
9.
Aghaeepour N, Chattopadhyay P, Ganesan A, ONeill K, Zare H, Jalali A, et al.
Bioinformatics
. 2012 Mar;
28(7):1009-16.
PMID: 22383736
Motivation: Polychromatic flow cytometry (PFC), has enormous power as a tool to dissect complex immune responses (such as those observed in HIV disease) at a single cell level. However, analysis...
10.
Hajiaghayi M, Condon A, Hoos H
BMC Bioinformatics
. 2012 Feb;
13:22.
PMID: 22296803
Background: RNA molecules play critical roles in the cells of organisms, including roles in gene regulation, catalysis, and synthesis of proteins. Since RNA function depends in large part on its...