Holger Gerhardt
Overview
Explore the profile of Holger Gerhardt including associated specialties, affiliations and a list of published articles.
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Articles
145
Citations
14650
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Recent Articles
1.
Schwanbeck J, Stahnke M, Eberlein A, Goeritzer M, Schulze A, Pernitsch D, et al.
JCI Insight
. 2025 Mar;
10(5).
PMID: 40059832
No abstract available.
2.
Giese W, Albrecht J, Oppenheim O, Akmeric E, Kraxner J, Schmidt D, et al.
Nat Commun
. 2025 Feb;
16(1):1474.
PMID: 39922822
Cell polarity involves the asymmetric distribution of cellular components such as signalling molecules and organelles within a cell, alterations in cell morphology and cell-cell contacts. Advances in fluorescence microscopy and...
3.
Zhao X, Sun Y, Zou J, Wu Y, Huang M, Kong H, et al.
Cell Death Differ
. 2025 Feb;
PMID: 39901038
GPX4-dependent ferroptosis has emerged as a therapeutic strategy for cancer treatment. Here, we demonstrated that protein kinase A (PKA) participates in the regulation of ferroptosis by controlling the mA modification...
4.
Oppenheim O, Giese W, Park H, Baumann E, Ivanov A, Beule D, et al.
bioRxiv
. 2025 Jan;
PMID: 39829872
Hereditary hemorrhagic telangiectasia is an autosomal dominant disorder caused by mutations in the bone morphogenetic protein signaling pathway, leading to arteriovenous malformations. While previously thought to share molecular and cellular...
5.
6.
Liegl G, Fischer F, N Martin C, Ronnefarth M, Blumrich A, Ahmadi M, et al.
Health Qual Life Outcomes
. 2024 Aug;
22(1):64.
PMID: 39148105
Background: Health-related quality of life (HRQL) has become an important outcome parameter in cardiology. The MOS 36-ltem Short-Form Health Survey (SF-36) and the PROMIS-29 are two widely used generic measures...
7.
Cano E, Schwarzkopf J, Kanda M, Lindberg E, Hollfinger I, Pogontke C, et al.
Circ Res
. 2024 Aug;
135(6):671-684.
PMID: 39092506
Background: The elaborate patterning of coronary arteries critically supports the high metabolic activity of the beating heart. How coronary endothelial cells coordinate hierarchical vascular remodeling and achieve arteriovenous specification remains...
8.
Mehl J, Farahani S, Brauer E, Klaus-Bergmann A, Thiele T, Ellinghaus A, et al.
Adv Sci (Weinh)
. 2024 Jan;
11(13):e2307050.
PMID: 38273642
Bone fracture healing is regulated by mechanobiological cues. Both, extracellular matrix (ECM) deposition and microvascular assembly determine the dynamics of the regenerative processes. Mechanical instability as by inter-fragmentary shear or...
9.
Dazzi C, Mehl J, Benamar M, Gerhardt H, Knaus P, Duda G, et al.
PLoS Comput Biol
. 2023 Nov;
19(11):e1011647.
PMID: 37956208
Sprouting angiogenesis plays a key role during bone regeneration. For example, insufficient early revascularization of the injured site can lead to delayed or non-healing. During sprouting, endothelial cells are known...
10.
Jin Y, Ding Y, Richards M, Kaakinen M, Giese W, Baumann E, et al.
Nat Cardiovasc Res
. 2023 Nov;
1(12):1156-1173.
PMID: 37936984
Vascular endothelial (VE)-cadherin in endothelial adherens junctions is an essential component of the vascular barrier, critical for tissue homeostasis and implicated in diseases such as cancer and retinopathies. Inhibitors of...