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Holger Bartsch

Explore the profile of Holger Bartsch including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
Citations 263
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Recent Articles
1.
Bachmann M, Bartsch T, Bippes C, Bachmann D, Puentes-Cala E, Bachmann J, et al.
Int J Mol Sci . 2021 Feb; 22(3). PMID: 33530489
Since the first description of nuclear autoantigens in the late 1960s and early 1970s, researchers, including ourselves, have found it difficult to establish monoclonal antibodies (mabs) against nuclear antigens, including...
2.
Demes M, Aszyk C, Bartsch H, Schirren J, Fisseler-Eckhoff A
Cancers (Basel) . 2016 Mar; 8(4). PMID: 27023611
Pulmonary malignancies with neuroendocrine differentiation represent a rare subclass of lung carcinomas, which vary in the extent of differentiation and grade of biological aggressiveness. In particular, neuroendocrine tumors are classified...
3.
Bartsch H, Bachmann M
Methods Mol Biol . 2015 Jul; 1314:173-8. PMID: 26139265
Sera of patients with systemic autoimmune diseases frequently contain autoantibodies to nuclear autoantigens. Immunoblotting of recombinant and native autoantigens is a commonly used technique for the identification and characterization of...
4.
Bartsch H, Franke C, Bachmann M
Methods Mol Biol . 2015 Jul; 1314:73-8. PMID: 26139256
Development of immunoblots is commonly performed using enzyme-labeled antibodies which convert soluble substrates into insoluble colored products. A simple, rapid, and sensitive alternative method which produces low background and allows...
5.
Franke C, Grafe D, Bartsch H, Bachmann M
Methods Mol Biol . 2015 Jul; 1314:63-71. PMID: 26139255
Many proteins bind to nucleic acids. For the first characterization of novel proteins, a fast and simple technique for testing their nucleic acid binding capabilities is desirable. Here we describe...
6.
Canzler U, Bartsch H, Grossmann K, Lehmann W, Conrad K, Kurien B, et al.
Methods Mol Biol . 2015 Jun; 1312:165-73. PMID: 26044001
Sera of tumor patients frequently contain autoantibodies to tumor associated antigens. Here we describe a miniaturized immunoblot platform allowing us to screen sera of patients for the presence of autoantibodies...
7.
Demes M, Scheil-Bertram S, Bartsch H, Fisseler-Eckhoff A
J Gastrointest Oncol . 2013 Jun; 4(2):182-92. PMID: 23730514
Background: Multiple activating mutations of the signal- and repair pathway, such as BRAF-, KRAS-mutations and microsatellite instabilities are involved in colorectal cancer pathogenesis. Molecular characterization of specifically locally advanced rectal...
8.
V Laffert M, Warth A, Penzel R, Schirmacher P, Jonigk D, Kreipe H, et al.
Lung Cancer . 2013 May; 81(2):200-6. PMID: 23669200
Background: The reliable identification of non-small cell lung cancers (NSCLC) with chromosomal breaks in the gene of the anaplastic lymphoma kinase (ALK) is crucial for the induction of therapy with...
9.
Bartsch H, Arndt C, Koristka S, Cartellieri M, Bachmann M
Methods Mol Biol . 2012 May; 869:481-6. PMID: 22585513
Although the main application for polyacrylamide gels is the separation and subsequent blotting of proteins for immunodetection, there are tasks that need staining of proteins in the polyacrylamide gel. Several...
10.
Arndt C, Koristka S, Feldmann A, Bartsch H, Bachmann M
Methods Mol Biol . 2012 May; 869:465-9. PMID: 22585511
Over the past, a series of staining procedures for proteins were published. The most commonly used staining dye for proteins is still Coomassie-Brilliant Blue. The major reason is Coomassie-Brilliant Blue...