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Hoku West-Foyle

Explore the profile of Hoku West-Foyle including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 205
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Recent Articles
1.
Du W, Zhou B, Forjaz A, Shin S, Wu F, Crawford A, et al.
bioRxiv . 2024 Jul; PMID: 39071324
Enrichment of tumor-associated macrophages (TAMΦs) in the tumor microenvironment correlates with worse clinical outcomes in triple-negative breast cancer (TNBC) patients, prompting the development of therapies to inhibit TAMΦ infiltration. However,...
2.
Yang E, Shen X, West-Foyle H, Hahm T, Siegler M, Brown D, et al.
Adv Sci (Weinh) . 2023 Nov; 10(35):e2304343. PMID: 37908150
Here, the authors report that co-crystallization of fluorophores with matrix-assisted laser desorption/ionization (MALDI) imaging matrices significantly enhances fluorophore brightness up to 79-fold, enabling the amplification of innate tissue autofluorescence. This...
3.
Jin Q, Bhatta A, Pagaduan J, Chen X, West-Foyle H, Liu J, et al.
Sci Adv . 2020 Apr; 6(13):eaaz2598. PMID: 32232160
Changes in structure and function of small muscular arteries play a major role in the pathophysiology of pulmonary hypertension, a burgeoning public health challenge. Improved anatomically mimetic in vitro models...
4.
Surcel A, Schiffhauer E, Thomas D, Zhu Q, DiNapoli K, Herbig M, et al.
Cancer Res . 2019 Jul; 79(18):4665-4678. PMID: 31358530
Metastasis is complex, involving multiple genetic, epigenetic, biochemical, and physical changes in the cancer cell and its microenvironment. Cells with metastatic potential are often characterized by altered cellular contractility and...
5.
Yang J, Bhattacharya S, West-Foyle H, Hung C, Wu T, Iglesias P, et al.
Nat Commun . 2019 Jan; 10(1):319. PMID: 30644399
In the original version of this Article, the label "RTK" in Figure 6a was inadvertently changed to "RTE". This has now been corrected in the PDF and HTML versions of...
6.
Yang J, Bhattacharya S, West-Foyle H, Hung C, Wu T, Iglesias P, et al.
Nat Commun . 2019 Jan; 10(1):318. PMID: 30644397
The original version of this Article contained an error in the spelling of the author Jr-Ming Yang, which was incorrectly given as J.-Ming Yang. This has now been corrected in...
7.
Yang J, Bhattacharya S, West-Foyle H, Hung C, Wu T, Iglesias P, et al.
Nat Commun . 2018 Nov; 9(1):4673. PMID: 30405112
The Ras-ERK signaling pathway regulates diverse cellular processes in response to environmental stimuli and contains important therapeutic targets for cancer. Recent single cell studies revealed stochastic pulses of ERK activation,...
8.
West-Foyle H, Kothari P, Osborne J, Robinson D
J Biol Chem . 2018 Mar; 293(18):6751-6761. PMID: 29549125
The 14-3-3 family comprises a group of small proteins that are essential, ubiquitous, and highly conserved across eukaryotes. Overexpression of the 14-3-3 proteins σ, ϵ, ζ, and η correlates with...
9.
Surcel A, Ng W, West-Foyle H, Zhu Q, Ren Y, Avery L, et al.
Proc Natl Acad Sci U S A . 2015 Jan; 112(5):1428-33. PMID: 25605895
Current approaches to cancer treatment focus on targeting signal transduction pathways. Here, we develop an alternative system for targeting cell mechanics for the discovery of novel therapeutics. We designed a...
10.
Ren Y, West-Foyle H, Surcel A, Miller C, Robinson D
Mol Biol Cell . 2014 Oct; 25(25):4150-65. PMID: 25318674
How myosin II localizes to the cleavage furrow in Dictyostelium and metazoan cells remains largely unknown despite significant advances in understanding its regulation. We designed a genetic selection using cDNA...