Ho-Sam Ahn
Overview
Explore the profile of Ho-Sam Ahn including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
14
Citations
150
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Clasby M, Chackalamannil S, Czarniecki M, Doller D, Eagen K, Greenlee W, et al.
Bioorg Med Chem Lett
. 2005 Dec;
16(6):1544-8.
PMID: 16380251
The design, synthesis, and SAR studies of a structurally novel series of highly potent thrombin receptor (PAR-1) antagonists are described. Compound 30 is a highly potent thrombin receptor antagonist (IC(50)=6.3...
12.
Chackalamannil S, Xia Y, Greenlee W, Clasby M, Doller D, Tsai H, et al.
J Med Chem
. 2005 Sep;
48(19):5884-7.
PMID: 16161991
Structurally novel thrombin receptor (protease activated receptor 1, PAR-1) antagonists based on the natural product himbacine are described. The prototypical PAR-1 antagonist 55 showed a Ki of 2.7 nM in...
13.
Chackalamannil S, Ahn H, Xia Y, Doller D, Foster C
Curr Med Chem Cardiovasc Hematol Agents
. 2004 Aug;
1(1):37-45.
PMID: 15317289
Protease activated receptor-1 (PAR-1), also known as thrombin receptor, is present in a variety of cell types such as platelets and endothelial cells. PAR-1 is proteolytically activated by thrombin by...
14.
Ahn H, Chackalamannil S, Boykow G, Graziano M, Foster C
Curr Pharm Des
. 2003 Oct;
9(28):2349-65.
PMID: 14529396
Thrombin, a plasma serine protease, plays a key role not only in coagulation and hemostasis but in thrombosis, restenosis and atherosclerosis. Thrombin activates platelets, endothelium, inflammatory cells and smooth muscle...