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Hisakazu Ogita

Explore the profile of Hisakazu Ogita including associated specialties, affiliations and a list of published articles. Areas
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Articles 91
Citations 2206
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Recent Articles
1.
Nishida M, Sato A, Shimizu A, Rahman N, Wada A, Kageyama S, et al.
Cancer Med . 2024 Oct; 13(19):e70276. PMID: 39377541
Background And Aims: Tumor growth and progression are affected by interactions between tumor cells and stromal cells within the tumor microenvironment. We previously showed that the expression of an integral...
2.
Imamura-Uehara Y, Yasuda-Yamahara M, Kuwagata S, Yamahara K, Yoshibayashi M, Tanaka-Sasaki Y, et al.
Biochem Biophys Rep . 2024 Jan; 37:101607. PMID: 38178924
Renal artery stenosis-induced chronic renal ischemia is an important cause of renal dysfunction, especially in older adults, and its incidence is currently increasing. To elucidate the mechanisms underlying chronic renal...
3.
Chi Soh J, Shimizu A, Sato A, Ogita H
Biochem Pharmacol . 2023 Oct; 218:115899. PMID: 37907138
Ras homolog gene family member A (RhoA) belongs to the Rho GTPase superfamily, which was first studied in cancers as one of the essential regulators controlling cellular function. RhoA has...
4.
Sato A, Tsukiyama T, Komeno M, Iwatani C, Tsuchiya H, Kawamoto I, et al.
Sci Rep . 2023 Sep; 13(1):15649. PMID: 37730951
Familial hypercholesterolemia (FH) is an inherited autosomal dominant disorder that is associated with a high plasma level of low-density lipoprotein (LDL) cholesterol, leading to an increased risk of cardiovascular diseases....
5.
Takashima S, Okamura E, Ichiyama Y, Nishi K, Shimizu A, Watanabe C, et al.
Exp Anim . 2023 Sep; 73(1):93-100. PMID: 37661429
Exocyst is an octameric protein complex implicated in exocytosis. The exocyst complex is highly conserved among mammalian species, but the physiological function of each subunit in exocyst remains unclear. Previously,...
6.
Chi Soh J, Shimizu A, Molla M, Zankov D, Nguyen L, Khan M, et al.
J Biol Chem . 2023 Feb; 299(3):102993. PMID: 36758801
Heart failure is one of the leading causes of death worldwide. RhoA, a small GTPase, governs actin dynamics in various tissue and cell types, including cardiomyocytes; however, its involvement in...
7.
Molla M, Shimizu A, Komeno M, Rahman N, Chi Soh J, Nguyen L, et al.
Commun Biol . 2022 Oct; 5(1):1071. PMID: 36207400
Whether a small GTPase RhoA plays a role in the pathology of abdominal aortic aneurysm (AAA) has not been determined. We show here that RhoA expression is reduced in human...
8.
Nakai S, Tateoka Y, Miyaguchi Y, Takahashi M, Ogita H
J Hum Lact . 2022 Jun; 39(2):315-324. PMID: 35658699
Background: Glutamic acid, an amino acid that exhibits umami taste, is utilized in Japanese food and is abundant in human milk. We examined the influence of maternal habitual eating behavior...
9.
Sato A, Rahman N, Shimizu A, Ogita H
Cancer Sci . 2021 Aug; 112(10):4005-4012. PMID: 34420253
Tumor growth and progression are complex processes mediated by mutual interactions between cancer cells and their surrounding stroma that include diverse cell types and acellular components, which form the tumor...
10.
Nguyen L, Shimizu A, Chi Soh J, Komeno M, Sato A, Ogita H
J Biochem . 2021 Jun; 170(5):577-585. PMID: 34086898
Transmembrane protein 168 (TMEM168) was found to be localized on the nuclear membrane. A heterozygous mutation (c.1616G>A, p. R539Q) in TMEM168 was identified in patients with Brugada syndrome. This mutation...