Hisaaki Taniguchi
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Explore the profile of Hisaaki Taniguchi including associated specialties, affiliations and a list of published articles.
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62
Citations
2438
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Recent Articles
1.
Kamiya Y, Nakashima T, Taniguchi T, Takahashi Y, Omura S, Taniguchi H
Biosci Biotechnol Biochem
. 2022 Sep;
86(12):1605-1614.
PMID: 36130200
Many useful natural products are usually screened based on their biological activities. On the other hand, various natural products can be detected based on their physicochemical properties. We have already...
2.
Phf5a regulates DNA repair in class switch recombination via p400 and histone H2A variant deposition
Begum N, Haque F, Stanlie A, Husain A, Mondal S, Nakata M, et al.
EMBO J
. 2021 May;
40(12):e106393.
PMID: 33938017
Antibody class switch recombination (CSR) is a locus-specific genomic rearrangement mediated by switch (S) region transcription, activation-induced cytidine deaminase (AID)-induced DNA breaks, and their resolution by non-homologous end joining (NHEJ)-mediated...
3.
Noda K, Kitagawa K, Miki T, Horiguchi M, Akama T, Taniguchi T, et al.
Sci Adv
. 2020 Nov;
6(48).
PMID: 33239290
Fibulin-4 is a matricellular protein required for extracellular matrix (ECM) assembly. Mice deficient in fibulin-4 ( ) have disrupted collagen and elastin fibers and die shortly after birth from aortic...
4.
Ohta S, Taniguchi T, Sato N, Hamada M, Taniguchi H, Rappsilber J
Mol Cell Proteomics
. 2018 Sep;
18(2):169-181.
PMID: 30266865
In mitosis, chromosomes achieve their characteristic shape through condensation, an essential process for proper segregation of the genome during cell division. A classical model for mitotic chromosome condensation proposes that...
5.
Sato N, Taniguchi T, Goda Y, Kosaka H, Higashino K, Sakai T, et al.
J Proteome Res
. 2016 Oct;
15(12):4709-4721.
PMID: 27748110
Connective tissues such as tendon, ligament and cartilage are mostly composed of extracellular matrix (ECM). These tissues are insoluble, mainly due to the highly cross-linked ECM proteins such as collagens....
6.
Husain A, Begum N, Taniguchi T, Taniguchi H, Kobayashi M, Honjo T
Nat Commun
. 2016 Feb;
7:10549.
PMID: 26842758
Topoisomerase 1, an enzyme that relieves superhelical tension, is implicated in transcription-associated mutagenesis and genome instability-associated with neurodegenerative diseases as well as activation-induced cytidine deaminase. From proteomic analysis of TOP1-associated...
7.
Sugawara A, Maita N, Gouda H, Yamamoto T, Hirose T, Kimura S, et al.
J Med Chem
. 2015 Jun;
58(12):4984-97.
PMID: 26030312
Argifin, a 17-membered pentapeptide, inhibits chitinase. As argifin has properties that render it unsuitable as a drug development candidate, we devised a mechanism to create the structural component of argifin...
8.
Hyodo K, Taniguchi T, Manabe Y, Kaido M, Mise K, Sugawara T, et al.
PLoS Pathog
. 2015 May;
11(5):e1004909.
PMID: 26020241
Eukaryotic positive-strand RNA [(+)RNA] viruses are intracellular obligate parasites replicate using the membrane-bound replicase complexes that contain multiple viral and host components. To replicate, (+)RNA viruses exploit host resources and...
9.
Kaido M, Abe K, Mine A, Hyodo K, Taniguchi T, Taniguchi H, et al.
PLoS Pathog
. 2014 Nov;
10(11):e1004505.
PMID: 25411849
The formation of virus movement protein (MP)-containing punctate structures on the cortical endoplasmic reticulum is required for efficient intercellular movement of Red clover necrotic mosaic virus (RCNMV), a bipartite positive-strand...
10.
Hirose T, Maita N, Gouda H, Koseki J, Yamamoto T, Sugawara A, et al.
Proc Natl Acad Sci U S A
. 2013 Sep;
110(40):15892-7.
PMID: 24043811
The Huisgen cycloaddition of azides and alkynes, accelerated by target biomolecules, termed "in situ click chemistry," has been successfully exploited to discover highly potent enzyme inhibitors. We have previously reported...