Hiroyoshi Kunimoto
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Explore the profile of Hiroyoshi Kunimoto including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
358
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Recent Articles
1.
Ichikawa K, Adachi S, Takase-Minegishi K, Nakayama Y, Nagasawa Y, Iizuka Y, et al.
Clin Exp Rheumatol
. 2025 Feb;
PMID: 39907597
Objectives: To characterise patients with trisomy 8 presenting with autoinflammatory features, comparing them to patients with Behçet's disease (BD). Methods: We comprehensively reviewed studies on trisomy 8-associated autoinflammatory symptoms from...
2.
Ikeda J, Shiba N, Kato S, Kunimoto H, Saito Y, Sagisaka M, et al.
Int J Hematol
. 2025 Feb;
PMID: 39891826
The prognosis of acute myeloid leukemia (AML) with KMT2A::MLLT3 rearrangement and MECOM overexpression and/or KRAS mutation is dismal, and the optimal treatment strategy remains unclear. However, to the best of...
3.
Kunimoto H, Sakuma T, Ohashi T, Shirafuta M, Teranaka H, Nakajima H
EJHaem
. 2024 Dec;
5(6):1335-1339.
PMID: 39691241
Anemia is a major clinical manifestation seen in myelodysplastic syndromes (MDS). Treatment options for anemia in low-risk MDS are limited. Especially, oral medication which is uniformly effective for anemia in...
4.
Momoi M, Katsumata Y, Kunimoto H, Inami T, Miya F, Anzai A, et al.
J Am Heart Assoc
. 2024 Nov;
13(23):e035498.
PMID: 39604025
Background: The cause of chronic thromboembolic pulmonary hypertension (CTEPH) remains largely unknown. Recently, clonal hematopoiesis (CH) has been reported to be associated with cardiovascular and thromboembolic diseases. Here, we investigated...
5.
Miyazaki T, Kamimura D, Wakamatsu M, Konishi M, Matsumura A, Teshigawara H, et al.
J Clin Exp Hematop
. 2024 Jul;
64(3):232-236.
PMID: 39085132
Erdheim-Chester disease (ECD) is a rare, non-Langerhans cell histiocytosis with diverse clinical features. It is characterized by systemic histiocyte infiltration of the bone, skin, central nervous system, lung, kidney, and...
6.
Kunimoto H
Rinsho Ketsueki
. 2024 Jun;
65(5):362-374.
PMID: 38825515
The epigenome regulates transcription of target genes through DNA methylation- or histone methylation/acetylation/phosphorylation/ubiquitination-mediated alteration of genomic function or chromatin conformation. Recent genomic studies have shown that multiple genes encoding epigenetic...
7.
Nakajima H, Kunimoto H
Int J Hematol
. 2024 May;
PMID: 38819628
VEXAS syndrome is a recently identified, adult-onset autoinflammatory disease caused by somatic mutations in UBA1. UBA1 is an X-linked gene encoding E1 ubiquitin activating enzyme and its mutation in hematopoietic...
8.
Kunimoto H
Rinsho Ketsueki
. 2024 Apr;
65(4):255-264.
PMID: 38684436
VEXAS syndrome is a new disease entity characterized by the presence of cytoplasmic vacuoles in blood cells, X-linked autoinflammatory symptoms, and somatic variants in UBA1, which encodes an E1 ubiquitin-activating...
9.
Ohashi T, Kunimoto H, Nukui J, Teshigawara H, Koyama S, Miyazaki T, et al.
Int J Hematol
. 2024 Mar;
119(5):603-607.
PMID: 38489090
Bloom syndrome (BS) is an autosomal recessive genetic disorder caused by variants in the BLM gene. BS is characterized by distinct facial features, elongated limbs, and various dermatological complications including...
10.
Knorr K, Rahman J, Erickson C, Wang E, Monetti M, Li Z, et al.
Nat Cancer
. 2023 Oct;
4(12):1675-1692.
PMID: 37872381
Despite recent advances in the treatment of acute myeloid leukemia (AML), there has been limited success in targeting surface antigens in AML, in part due to shared expression across malignant...