Hiroshi Yanagawa
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Explore the profile of Hiroshi Yanagawa including associated specialties, affiliations and a list of published articles.
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128
Citations
3713
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Recent Articles
1.
Ide M, Tabata N, Murai K, Yonemura Y, Wang Y, Ishida A, et al.
FEBS Lett
. 2025 Jan;
PMID: 39865491
Hepatitis B virus (HBV) infects cells by attaching to heparan sulfate proteoglycans (HSPG) and Na/taurocholate cotransporting polypeptide (NTCP). The endothelial lipase LIPG bridges HSPG and HBV, facilitating HBV attachment. From...
2.
Ide M, Tabata N, Yonemura Y, Murai K, Wang Y, Ishida A, et al.
Microbiol Spectr
. 2024 Jan;
12(3):e0378523.
PMID: 38240571
Overcoming hepatitis B virus (HBV) is a challenging problem because HBV deceives the host immune system. We have found that DENN domain-containing 2A (DENND2A) was essential for HBV maintenance, although...
3.
Shirasaki T, Murai K, Ishida A, Kuroki K, Kawaguchi K, Wang Y, et al.
Hepatol Commun
. 2023 Sep;
7(9).
PMID: 37655967
Background: HBV infection causes chronic liver disease and leads to the development of HCC. To identify host factors that support the HBV life cycle, we previously established the HC1 cell...
4.
Li Y, Kuroki K, Shimakami T, Murai K, Kawaguchi K, Shirasaki T, et al.
Cell Mol Gastroenterol Hepatol
. 2022 Oct;
15(3):533-558.
PMID: 36270602
Background & Aims: Hepatitis B virus (HBV) infection is difficult to cure owing to the persistence of covalently closed circular viral DNA (cccDNA). We performed single-cell transcriptome analysis of newly...
5.
Ide M, Tabata N, Yonemura Y, Shirasaki T, Murai K, Wang Y, et al.
J Biol Chem
. 2022 Jun;
298(7):102097.
PMID: 35660020
Hepatitis B virus (HBV) infection is a major global health problem with no established cure. Dedicator of cytokinesis 11 (DOCK11), known as a guanine nucleotide exchange factor (GEF) for Cdc42,...
6.
Ichikawa D, Nakamura M, Murota W, Osawa S, Matsushita M, Yanagawa H, et al.
Biochem Biophys Res Commun
. 2019 Oct;
521(1):252-258.
PMID: 31653349
To date, the prognosis of multiple myeloma (MM) in patients harboring cytogenetic abnormalities (CA) involving t (4; 14) and deletion of chromosome 17 remains poor despite recent advances in drug...
7.
Hayashi M, Madokoro H, Yamada K, Nishida H, Morimoto C, Sakamoto M, et al.
Cancers (Basel)
. 2019 Aug;
11(8).
PMID: 31398954
Here, we report a novel antibody drug conjugate (ADC) with the humanized anti-CD26 monoclonal antibody YS110 and triptolide (TR-1). YS110 has an inhibitory activity against the CD26-positive tumor growth via...
8.
Yamada T, Hayashi T, Hikiri S, Kobayashi N, Yanagawa H, Ikeguchi M, et al.
J Chem Inf Model
. 2019 Jul;
59(8):3533-3544.
PMID: 31282659
An oncoprotein MDM2 binds to the extreme N-terminal peptide region of a tumor suppressor protein p53 (p53NTD) and inhibits its anticancer activity. We recently discovered a peptide named MIP which...
9.
Kido S, Ae R, Kosami K, Matsubara Y, Makino N, Sasahara T, et al.
Pediatr Int
. 2019 Apr;
61(6):539-543.
PMID: 30980447
Background: Evidence suggests that seasonal variation in the onset of Kawasaki disease (KD) exists worldwide. Whether a seasonal component to successful i.v. immunoglobulin (IVIG) therapy exists in KD-positive children, however,...
10.
Makino N, Nakamura Y, Yashiro M, Kosami K, Matsubara Y, Ae R, et al.
Pediatr Int
. 2019 Feb;
61(4):397-403.
PMID: 30786118
Background: Approximately 50 years have passed since Kawasaki disease (KD) was first reported. The KD nationwide survey began in 1970. Although >360 000 cases have already been reported in Japan,...