Hiroshi Hashimoto
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Explore the profile of Hiroshi Hashimoto including associated specialties, affiliations and a list of published articles.
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388
Citations
4489
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Recent Articles
1.
Yamauchi Y, Sato M, Iwata T, Endo M, Ikeda N, Hashimoto H, et al.
Cancers (Basel)
. 2024 Oct;
16(19).
PMID: 39409952
Background/objectives: The efficacy of lung metastasectomy in patients with urothelial carcinoma remains inconclusive, as there is only limited evidence from small studies. In this study, we aimed to assess the...
2.
Kakegawa T, Sugimoto K, Kamiyama N, Hashimoto H, Takahashi H, Wada T, et al.
Ultrasonography
. 2024 Oct;
43(6):457-468.
PMID: 39370861
Purpose: The study aimed to compare the diagnostic performance of washout-parametric imaging (WOPI) with that of conventional contrast-enhanced ultrasound (cCEUS) in differentiating focal liver lesions (FLLs). Methods: A total of...
3.
Kobayashi T, Oishi S, Matsui M, Hara K, Hashimoto H, Watanabe K, et al.
PNAS Nexus
. 2024 Jul;
3(7):pgae265.
PMID: 39035040
Tyrosine phenol-lyase (TPL), which is expressed in intestinal bacteria, catalyzes the formation of phenol from the substrate L-Tyr. Bacterial metabolite phenol and the sulfate conjugate (phenyl sulfate) are known as...
4.
Ito K, Ogawa T, Tanigaki T, Kameda K, Hashimoto H, Kawana A, et al.
Respir Med Case Rep
. 2024 Jul;
51:102075.
PMID: 39006194
Eosinophilic pleural effusion is rare, and the cause is often obscure. A 73-year-old man with no relevant medical history presented with exertional dyspnea. Chest imaging revealed left-sided pleural effusion, and...
5.
Nakahara M, Watanabe S, Sato M, Okumura H, Kawatani M, Osada H, et al.
Biochemistry
. 2024 May;
63(10):1241-1245.
PMID: 38724483
Natural products are important sources of seed compounds for drug discovery. However, it has become difficult in recent years to discover new compounds with valuable pharmacological activities. On the other...
6.
Hara K, Tatsukawa K, Nagata K, Iida N, Hishiki A, Ohashi E, et al.
J Biol Chem
. 2024 Feb;
300(3):105751.
PMID: 38354779
Eukaryotic DNA clamp is a trimeric protein featuring a toroidal ring structure that binds DNA on the inside of the ring and multiple proteins involved in DNA transactions on the...
7.
Sato M, Sakano S, Nakahara M, Tamura Y, Hara K, Hashimoto H, et al.
J Am Chem Soc
. 2023 Dec;
145(49):26883-26889.
PMID: 38051581
(-)-FR901483 () isolated from the fungus sp. No.11231 achieves immunosuppression via nucleic acid biosynthesis inhibition rather than IL-2 production inhibition as accomplished by FK506 and cyclosporin A. Recently, we identified...
8.
Watari R, Sawada H, Hashimoto H, Kasai Y, Oka R, Shimizu R, et al.
J Pharm Sci
. 2023 Sep;
113(3):798-805.
PMID: 37742997
Coproporphyrin-I (CP-I) has been investigated as an endogenous biomarker of organic anion transporting polypeptide (OATP) 1B. Here, we determined the CP-I concentrations in a cocktail drug-drug interaction (DDI) study of...
9.
Hashimoto H, Tamura Y, Yamada K, Katoh Y, Shimada T, Fujiwara R, et al.
Rinsho Ketsueki
. 2023 Sep;
64(8):746-750.
PMID: 37673626
A 72-year-old man with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL) was treated with dasatinib (week1: 50 mg/day, week2: 70 mg/day, week3-: 100 mg/day) and prednisolone from June 2017. However, in...
10.
Kawasaki A, Kusumawati P, Kawamura Y, Kondo Y, Kusaoi M, Amano H, et al.
RMD Open
. 2023 May;
9(2).
PMID: 37258043
Objective: Major histocompatibility complex strongly contributes to susceptibility to systemic lupus erythematosus (SLE). In the European populations, and are susceptibility alleles, but locus was reported to account for the association...