Hirokazu Mizoguchi
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Explore the profile of Hirokazu Mizoguchi including associated specialties, affiliations and a list of published articles.
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76
Citations
438
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Recent Articles
1.
Yoshizumi M, Ise S, Yonezawa A, Watanabe C, Sakurada S, Mizoguchi H
Basic Clin Pharmacol Toxicol
. 2024 Feb;
134(5):704-711.
PMID: 38409579
Although α-adrenoceptor (α-AR) antagonists used to treat benign prostatic hyperplasia can cause ejaculation disorders, the aetiology of this adverse event is still controversial. Therefore, we investigated the effects of antagonists...
2.
Yoshizumi M, Tazawa N, Watanabe C, Mizoguchi H
Front Immunol
. 2023 Jan;
13:1080302.
PMID: 36618411
Chronic inflammation in the urinary bladder is a potential risk factor for bladder dysfunction, including interstitial cystitis/bladder pain syndrome (IC/BPS). Although several studies have reported that activation of transient receptor...
3.
Translational Value of the Transdermal Administration of Bergamot Essential Oil and of Its Fractions
Scuteri D, Rombola L, Crudo M, Watanabe C, Mizoguchi H, Sakurada S, et al.
Pharmaceutics
. 2022 May;
14(5).
PMID: 35631592
The essential oil of bergamot (BEO) has consistently proven antinociceptive and antiallodynic properties. Accordingly, the analgesic efficacy of the decolored essential oil (DEC), with higher levels of limonene, and the...
4.
Scuteri D, Rombola L, Crudo M, Watanabe C, Mizoguchi H, Sakurada S, et al.
Pharmaceutics
. 2022 Feb;
14(2).
PMID: 35214045
Bergamot essential oil (BEO) is endowed with consistent and reproducible antinociceptive and anti-allodynic properties when administered via an inhalation route. However, the effects of its main constituents and of its...
5.
Iio K, Kutsumura N, Nagumo Y, Saitoh T, Tokuda A, Hashimoto K, et al.
Bioorg Med Chem Lett
. 2021 Dec;
56:128485.
PMID: 34861349
Mas-related G protein-coupled receptor X2 (MRGPRX2) mediates the itch response in neurons and is involved in atopic dermatitis (AD)-associated inflammation and itch. Potent and MRGPRX2-selective ligands are essential to an...
6.
Scuteri D, Cassano R, Trombino S, Russo R, Mizoguchi H, Watanabe C, et al.
Pharmaceutics
. 2021 Apr;
13(3).
PMID: 33809385
Dementia is one of the most common causes of disability worldwide characterized by memory loss, cognitive impairment, and behavioral and psychological symptoms (BPSD), including agitation. Treatment of the latter consists...
7.
Watanabe C, Komiyama A, Yoshizumi M, Sakurada S, Mizoguchi H
Front Pharmacol
. 2020 Dec;
11:593647.
PMID: 33343363
The antinociceptive effect of methadone in the morphine-resistant inflammatory pain state was described in the paw-withdrawal test using the complete Freund's adjuvant (CFA)-induced mouse inflammatory pain model. After intraplantar (i.pl.)...
8.
Yoshizumi M, Watanabe C, Mizoguchi H
Pharmacol Res Perspect
. 2020 Dec;
9(1):e00697.
PMID: 33340266
Although interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic condition causing bladder pain and urinary symptoms, effective treatments have not been established. The aim of this study was to adapt...
9.
Yoshizumi M, Yonezawa A, Kimura Y, Watanabe C, Sakurada S, Mizoguchi H
J Sex Med
. 2020 Nov;
18(2):231-239.
PMID: 33243689
Background: We previously reported that the combination of the dopamine (DA) receptor agonist apomorphine and the 5-hydroxytryptamine (5-HT) receptor agonist m-chlorophenylpiperazine (m-CPP) in rats potently and selectively facilitates the ejaculatory...
10.
Mizoguchi H, Fujii H
Curr Top Med Chem
. 2020 Sep;
20(31):2866-2877.
PMID: 32962616
Since a μ-opioid receptor gene containing multiple exons has been identified, the variety of splice variants for μ-opioid receptors have been reported in various species. Amidino-TAPA and IBNtxA have been...