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Hiroaki Shimomura

Explore the profile of Hiroaki Shimomura including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 169
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Recent Articles
1.
Sakisaka N, Mitani K, Sempuku S, Imai T, Takemoto Y, Shimomura H, et al.
Front Nutr . 2018 Oct; 5:73. PMID: 30320119
Frailty in older people is strongly associated with poor nutrition, which is particularly important in the present-day superaging society. This study initially investigated a number of cases of frailty where...
2.
Terasaki F, Morita H, Harada-Shiba M, Ohta N, Otsuka K, Nogi S, et al.
Intern Med . 2013 Mar; 52(5):577-81. PMID: 23448768
We herein report the case of a 53-year-old man with severe coronary ischemia who underwent successful coronary artery bypass surgery. Of note, he had hypercholesterolemia and presented with multiple large...
3.
Otsuka K, Terasaki F, Shimomura H, Tsukada B, Horii T, Isomura T, et al.
Heart Vessels . 2010 Sep; 25(6):474-84. PMID: 20878407
The ubiquitin (Ub)-proteasome system (UPS) is an important proteolytic mechanism for selecting and digesting cytotoxic proteins. The aim of this study is to elucidate expression and in situ localization of...
4.
Tsukada B, Terasaki F, Shimomura H, Otsuka K, Otsuka K, Katashima T, et al.
Hum Pathol . 2009 Mar; 40(7):1015-22. PMID: 19297005
The objectives of this study were to analyze the incidence of chronic myocarditis in dilated cardiomyopathy and to evaluate the diagnostic value of tenascin C for assessing inflammatory activity in...
5.
Terasaki F, Ukimura A, Tsukada B, Fujita S, Katashima T, Otsuka K, et al.
Circ J . 2008 Jul; 72(8):1303-7. PMID: 18654018
Background: Various cytokines are involved in the pathogenesis of sarcoidosis, but their expression in the myocardium has not been documented for cardiac sarcoidosis. Methods And Results: Myocardial tissue was obtained...
6.
Otsuka K, Terasaki F, Eishi Y, Shimomura H, Ogura Y, Horii T, et al.
Circ J . 2007 Nov; 71(12):1937-41. PMID: 18037750
Background: Cardiac sarcoidosis is frequently overlooked or misdiagnosed as idiopathic dilated cardiomyopathy (DCM), primarily because of difficulties in its diagnosis. This is a crucial issue because appropriate therapy with immunosuppressive...
7.
Terasaki F, Fujita M, Shimomura H, Tsukada B, Otsuka K, Otsuka K, et al.
Circ J . 2007 Sep; 71(10):1545-50. PMID: 17895549
Background: The myeloid-related protein complex (MRP8/14) is expressed in activated human macrophages and reported to be involved in the inflammatory process. The expression of MRP8/14 in patients with cardiac sarcoidosis...
8.
Otsuka K, Terasaki F, Iimori A, Tonari S, Shimomura H, Ito T, et al.
Heart Vessels . 2007 May; 22(3):208-10. PMID: 17533527
Cardiac blood cysts are rarely seen in adult patients and in the right atrium. The origin of cardiac blood cysts is not understood, and several hypotheses have been proposed. We...
9.
Terasaki F, Okamoto H, Onishi K, Sato A, Shimomura H, Tsukada B, et al.
Circ J . 2007 Feb; 71(3):327-30. PMID: 17322629
Background: Tenascin-C (TN-C), an extracellular matrix glycoprotein, is specifically expressed at high levels during embryonic development, but not in the adult heart. TN-C reappears at sites of inflammatory tissue remodeling...
10.
Mori T, Hayashi T, Sohmiya K, Okuda N, Shimomura H, Ohkita M, et al.
Circ J . 2005 Apr; 69(5):596-602. PMID: 15849448
Background: Both beta-adrenergic blockers and angiotensin-II receptor blockers were reported to improve the prognosis of patients with heart failure, but the efficacy of combination therapy with these agents has not...