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Hiroaki Iio

Explore the profile of Hiroaki Iio including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Mori Y, Akizuki Y, Honda R, Takao M, Tsuchimoto A, Hashimoto S, et al.
Nat Commun . 2024 Jul; 15(1):5379. PMID: 38956052
Targeted protein degradation is a groundbreaking modality in drug discovery; however, the regulatory mechanisms are still not fully understood. Here, we identify cellular signaling pathways that modulate the targeted degradation...
2.
Iriki T, Iio H, Yasuda S, Masuta S, Kato M, Kosako H, et al.
Cell Rep . 2023 Aug; 42(8):112880. PMID: 37541257
The proteasome plays a central role in intracellular protein degradation. Age-dependent decline in proteasome activity is associated with cellular senescence and organismal aging; however, the mechanism by which the proteasome...