Hiren R Modi
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Explore the profile of Hiren R Modi including associated specialties, affiliations and a list of published articles.
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33
Citations
299
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Recent Articles
1.
Musyaju S, Modi H, Shear D, Scultetus A, Pandya J
Int J Mol Sci
. 2025 Feb;
26(3).
PMID: 39940675
Traumatic brain injury (TBI) results from external mechanical forces exerted on the brain, triggering secondary injuries due to cellular excitotoxicity. A key indicator of damage is mitochondrial dysfunction, which is...
2.
Modi H, Musyaju S, Ratcliffe M, Shear D, Scultetus A, Pandya J
Antioxidants (Basel)
. 2024 Mar;
13(3).
PMID: 38539837
Traumatic brain injury (TBI) is a major global health problem that affects both civilian and military populations worldwide. Post-injury acute, sub-acute, and chronic progression of secondary injury processes may contribute...
3.
Pandya J, Musyaju S, Modi H, Okada-Rising S, Bailey Z, Scultetus A, et al.
J Transl Med
. 2024 Feb;
22(1):167.
PMID: 38365798
Targeting drugs to the mitochondrial level shows great promise for acute and chronic treatment of traumatic brain injury (TBI) in both military and civilian sectors. Perhaps the greatest obstacle to...
4.
Musyaju S, Modi H, Flerlage W, Scultetus A, Shear D, Pandya J
Anal Biochem
. 2023 Sep;
680:115301.
PMID: 37673410
Owing to evidence that mitochondrial dysfunction plays a dominant role in the traumatic brain injury (TBI) pathophysiology, the Western blot (WB) based immunoblotting method is widely employed to identify changes...
5.
Shen Y, Wang Q, Modi H, Pathak A, Geocadin R, Thakor N, et al.
Ann Biomed Eng
. 2023 May;
51(8):1847-1858.
PMID: 37184745
Cerebral vascular autoregulation is impaired following resuscitation from cardiac arrest (CA), and its quantification may allow assessing CA-induced brain injury. However, hyperemia occurring immediately post-resuscitation limits the application of most...
6.
Pandya J, Musyaju S, Modi H, Cao Y, Flerlage W, Huynh L, et al.
Free Radic Biol Med
. 2023 Feb;
198:44-58.
PMID: 36758906
Traumatic Brain Injury (TBI) is caused by the external physical assaults damages the brain. It is a heterogeneous disorder that remains a leading cause of death and disability in the...
7.
Modi H, Wang Q, Olmstead S, Khoury E, Sah N, Guo Y, et al.
Bioeng Transl Med
. 2022 Jan;
7(1):e10259.
PMID: 35079634
Cardiac arrest (CA), the sudden cessation of effective cardiac pumping function, is still a major clinical problem with a high rate of early and long-term mortality. Post-cardiac arrest syndrome (PCAS)...
8.
Guo Y, Cho S, Wei Z, Wang Q, Modi H, Gharibani P, et al.
Neurocrit Care
. 2022 Jan;
37(1):60-72.
PMID: 35072925
Background: Cerebral blood flow (CBF) plays an important role in neurological recovery after cardiac arrest (CA) resuscitation. However, the variations of CBF recovery in distinct brain regions and its correlation...
9.
Sherman D, Williams A, Gd S, Modi H, Wang Q, Thakor N, et al.
Crit Care Explor
. 2021 Feb;
3(2):e0349.
PMID: 33634267
Objectives: Prolonged cardiac arrest is known to cause global ischemic brain injury and functional impairment. Upon resuscitation, electroencephalographic recordings of brain activity begin to resume and can potentially be used...
10.
Wei Z, Wang Q, Modi H, Cho S, Geocadin R, Thakor N, et al.
NMR Biomed
. 2020 Jul;
33(11):e4377.
PMID: 32662593
Brain injury following cardiac arrest (CA) is thought to be caused by a sudden loss of blood flow resulting in disruption in oxygen delivery, neural function and metabolism. However, temporal...