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Hiral Patel

Explore the profile of Hiral Patel including associated specialties, affiliations and a list of published articles. Areas
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Articles 53
Citations 880
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Recent Articles
1.
Frasier K, Herrick G, Patel H, Kakarla S, Danial L, Konagalla S, et al.
Cureus . 2024 Dec; 16(11):e72986. PMID: 39640154
Retention in dermatological clinical trials is critical for ensuring the validity and reliability of study outcomes, yet participant dropout remains a pervasive challenge. In this analysis, the primary aim is...
2.
Wu K, Patel H, Wu H, Quintanilla M, Bennett M, Sala S, et al.
bioRxiv . 2024 Jul; PMID: 39026829
Myosin 2 dynamically assembles into filaments that exert force on the actin cytoskeleton. To form filaments, myosin 2 monomers transition between folded and unfolded states. Monomer unfolding exposes an extended...
3.
Lumpkin C, Patel H, Potts G, Chaurasia S, Gibilisco L, Srivastava G, et al.
Mol Brain . 2024 May; 17(1):26. PMID: 38778381
Aggregation of misfolded α-synuclein (α-syn) is a key characteristic feature of Parkinson's disease (PD) and related synucleinopathies. The nature of these aggregates and their contribution to cellular dysfunction is still...
4.
Nicol B, Vandenbossche-Goddard E, Thorpe C, Newman R, Patel H, Yates D
Toxicology . 2024 May; 505:153826. PMID: 38719068
With the move away from safety testing assessment based on data generated in experimental animals the concept of Next Generation Risk Assessment (NGRA) has arisen which instead uses data from...
5.
Rathod M, Patel H, Gajjar D
J Vis Exp . 2024 Apr; (205). PMID: 38557954
Pseudomonas aeruginosa (P. aeruginosa) is known for its production of a diverse range of virulence factors to establish infections in the host. One such mechanism is the scavenging of iron...
6.
Quintanilla M, Patel H, Wu H, Sochacki K, Chandrasekar S, Akamatsu M, et al.
J Cell Biol . 2024 Feb; 223(4). PMID: 38353656
The ability to dynamically assemble contractile networks is required throughout cell physiology, yet direct biophysical mechanisms regulating non-muscle myosin 2 filament assembly in living cells are lacking. Here, we use...
7.
Sharma S, Luo M, Patel H, Mueller D, Liao M
Nat Struct Mol Biol . 2024 Feb; 31(4):657-666. PMID: 38316880
Mitochondrial adenosine triphosphate (ATP) synthase uses the proton gradient across the inner mitochondrial membrane to synthesize ATP. Structural and single molecule studies conducted mostly at neutral or basic pH have...
8.
Liu L, Malagu K, Haughan A, Khetarpal V, Stott A, Esmieu W, et al.
J Med Chem . 2023 Sep; 66(18):13205-13246. PMID: 37712656
Huntington's disease (HD) is caused by an expanded CAG trinucleotide repeat in exon 1 of the huntingtin () gene. We report the design of a series of pre-mRNA splicing modulators...
9.
Mansuri Z, Dhuvad J, Anchlia S, Bhatt U, Rajpoot D, Patel H
Natl J Maxillofac Surg . 2023 Sep; 14(2):256-263. PMID: 37661972
Background: The principal transfacial routes described to approach condylar process fractures are preauricular, retromandibular, high submandibular, and their various modifications. The selection of a specific surgical approach mainly depends on...
10.
Taghavi T, Patel H, Rafie R
Plants (Basel) . 2023 May; 12(9). PMID: 37176888
Anthocyanins are a major group of plant pigments that have antioxidant activities. Pigments play a major role in human health and have attracted a lot of attention globally. Many factors...