Hila Doron
Overview
Explore the profile of Hila Doron including associated specialties, affiliations and a list of published articles.
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10
Citations
447
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Recent Articles
1.
Adler O, Zait Y, Cohen N, Blazquez R, Doron H, Monteran L, et al.
Nat Cancer
. 2023 Feb;
4(3):401-418.
PMID: 36797502
Brain metastasis still encompass very grim prognosis and therefore understanding the underlying mechanisms is an urgent need toward developing better therapeutic strategies. We uncover the intricate interactions between recruited innate...
2.
Monteran L, Ershaid N, Doron H, Zait Y, Scharff Y, Ben-Yosef S, et al.
Nat Commun
. 2022 Oct;
13(1):5797.
PMID: 36184683
Mortality from breast cancer is almost exclusively a result of tumor metastasis and resistance to therapy and therefore understanding the underlying mechanisms is an urgent challenge. Chemotherapy, routinely used to...
3.
Sheinboim D, Parikh S, Manich P, Markus I, Dahan S, Parikh R, et al.
Cancer Res
. 2022 Sep;
82(22):4164-4178.
PMID: 36084256
Significance: Exercise protects against cancer progression and metastasis by inducing a high nutrient demand in internal organs, indicating that reducing nutrient availability to tumor cells represents a potential strategy to...
4.
Toker I, Lev I, Mor Y, Gurevich Y, Fisher D, Houri-Zeevi L, et al.
Dev Cell
. 2022 Feb;
57(3):298-309.e9.
PMID: 35134343
It is unknown whether transient transgenerational epigenetic responses to environmental challenges affect the process of evolution, which typically unfolds over many generations. Here, we show that in C. elegans, inherited...
5.
Ershaid N, Sharon Y, Doron H, Raz Y, Shani O, Cohen N, et al.
Nat Commun
. 2019 Sep;
10(1):4375.
PMID: 31558756
Cancer-Associated Fibroblasts (CAFs) were shown to orchestrate tumour-promoting inflammation in multiple malignancies, including breast cancer. However, the molecular pathways that govern the inflammatory role of CAFs are poorly characterised. In...
6.
Doron H, Amer M, Ershaid N, Blazquez R, Shani O, Lahav T, et al.
Cell Rep
. 2019 Aug;
28(7):1785-1798.e6.
PMID: 31412247
Melanoma is the deadliest skin cancer due to its high rate of metastasis, frequently to the brain. Brain metastases are incurable; therefore, understanding melanoma brain metastasis is of great clinical...
7.
Conniot J, Scomparin A, Peres C, Yeini E, Pozzi S, Matos A, et al.
Nat Nanotechnol
. 2019 Aug;
14(9):891-901.
PMID: 31384037
A low response rate, acquired resistance and severe side effects have limited the clinical outcomes of immune checkpoint therapy. Here, we show that combining cancer nanovaccines with an anti-PD-1 antibody...
8.
Lahav T, Adler O, Zait Y, Shani O, Amer M, Doron H, et al.
Int J Cancer
. 2019 Jun;
145(9):2521-2534.
PMID: 31216364
The major cause of melanoma mortality is metastasis to distant organs, including lungs and brain. Reciprocal interactions of metastasizing tumor cells with stromal cells in secondary sites play a critical...
9.
Doron H, Pukrop T, Erez N
Cancer Res
. 2019 Jan;
79(3):423-436.
PMID: 30679177
Brain metastases are more common than primary CNS tumors and confer grave prognosis on patients, as existing treatments have very limited efficacy. The tumor microenvironment has a central role in...
10.
Blau R, Epshtein Y, Pisarevsky E, Tiram G, Israeli Dangoor S, Yeini E, et al.
Theranostics
. 2018 Jul;
8(13):3437-3460.
PMID: 30026858
Complete tumor removal during surgery has a great impact on patient survival. To that end, the surgeon should detect the tumor, remove it and validate that there are no residual...