Anna Scomparin
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Explore the profile of Anna Scomparin including associated specialties, affiliations and a list of published articles.
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44
Citations
596
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Recent Articles
1.
Koshrovski-Michael S, Ajamil D, Dey P, Kleiner R, Tevet S, Epshtein Y, et al.
Sci Adv
. 2024 Dec;
10(50):eadr4762.
PMID: 39671487
Combined therapies in cancer treatment aim to enhance antitumor activity. However, delivering multiple small molecules imposes challenges, as different drugs have distinct pharmacokinetic profiles and tumor penetration abilities, affecting their...
2.
Di Cintio F, Argenziano M, Scomparin A, Capolla S, Busato D, Steffe A, et al.
Nanomedicine (Lond)
. 2024 Dec;
20(1):23-36.
PMID: 39620421
Background: Recently, we developed AT101, an IgM-class mouse monoclonal antibody directed against glypican-1 (GPC1), a proteoglycan that can be considered as useful target for glioblastoma multiforme (GBM) treatment being specifically...
3.
Misrakli M, Rizzo S, Bordano V, Bozza A, Ferraris L, Marini E, et al.
Materials (Basel)
. 2024 Oct;
17(20).
PMID: 39459664
Nasal delivery is a non-invasive strategy for effective drug delivery. Nevertheless, in order to promote drug uptake by the nasal mucosa, it is fundamental to increase its residence time in...
4.
Liubomirski Y, Tiram G, Scomparin A, Gnaim S, Das S, Gholap S, et al.
J Control Release
. 2024 Jan;
367:148-157.
PMID: 38228272
Antibody-drug conjugates (ADCs) are a rapidly expanding class of anticancer therapeutics, with 14 ADCs already approved worldwide. We developed unique linker technologies for the bioconjugation of drug molecules with controlled-release...
5.
Puricelli C, Gigliotti C, Stoppa I, Sacchetti S, Pantham D, Scomparin A, et al.
Pharmaceutics
. 2023 Jun;
15(6).
PMID: 37376219
Chronic inflammation contributes to the pathogenesis of many diseases, including apparently unrelated conditions such as metabolic disorders, cardiovascular diseases, neurodegenerative diseases, osteoporosis, and tumors, but the use of conventional anti-inflammatory...
6.
Molinar C, Tannous M, Meloni D, Cavalli R, Scomparin A
Macromol Biosci
. 2023 May;
23(9):e2300102.
PMID: 37212473
The efficacious delivery of therapeutic nucleic acids to cancer still remains an open issue. Through the years, several strategies are developed for the encapsulation of genetic molecules exploiting different materials,...
7.
Pozzi S, Scomparin A, Ben-Shushan D, Yeini E, Ofek P, Nahmad A, et al.
JCI Insight
. 2022 Aug;
7(17).
PMID: 35980743
Development of resistance to chemo- and immunotherapies often occurs following treatment of melanoma brain metastasis (MBM). The brain microenvironment (BME), particularly astrocytes, cooperate toward MBM progression by upregulating secreted factors,...
8.
Pisarevsky E, Blau R, Epshtein Y, Ben-Shushan D, Eldar-Boock A, Tiram G, et al.
Adv Ther (Weinh)
. 2022 Jun;
3(8).
PMID: 35754977
Targeted therapies against cancer can relieve symptoms and induce remission, however, they often present limited duration of disease control, cause side effects and often induce acquired resistance. Therefore, there is...
9.
Argenziano M, Occhipinti S, Scomparin A, Angelini C, Novelli F, Soster M, et al.
Drug Deliv Transl Res
. 2022 Jun;
12(8):2007-2018.
PMID: 35672651
Immunotherapy is a valuable approach to cancer treatment as it is able to activate the immune system. However, the curative methods currently in clinical practice, including immune checkpoint inhibitors, present...
10.
Argenziano M, Ansari I, Muntoni E, Spagnolo R, Scomparin A, Cavalli R
Antioxidants (Basel)
. 2022 May;
11(5).
PMID: 35624871
-resveratrol, a polyphenolic phytoalexin found in various plant sources, has been the focus of increasing attention in recent years because of its role in the prevention of many human diseases,...