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Hideki Horikawa

Explore the profile of Hideki Horikawa including associated specialties, affiliations and a list of published articles. Areas
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Articles 22
Citations 560
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Recent Articles
1.
Nakatochi M, Kushima I, Aleksic B, Kimura H, Kato H, Inada T, et al.
Psychiatry Clin Neurosci . 2024 Oct; 79(1):12-20. PMID: 39403837
Aim: Bipolar disorder (BD) is a common psychiatric disorder characterized by alterations between manic/hypomanic and depressive states. Rare pathogenic copy number variations (CNVs) that overlap with exons of synaptic genes...
2.
Kushima I, Nakatochi M, Aleksic B, Okada T, Kimura H, Kato H, et al.
Biol Psychiatry . 2022 Jun; 92(5):362-374. PMID: 35667888
Background: We aimed to determine the similarities and differences in the roles of genic and regulatory copy number variations (CNVs) in bipolar disorder (BD), schizophrenia (SCZ), and autism spectrum disorder...
3.
Hayakawa K, Watabe M, Horikawa H, Sato-Kasai M, Shimokawa N, Nakao T, et al.
J Pers Med . 2022 Feb; 12(2). PMID: 35207620
Lower serum levels of low-density lipoprotein cholesterol (LDL-C) have been suggested to indicate higher suicide risk and various psychiatric symptoms. Previously, we reported that lower serum LDL-C levels are associated...
4.
Isomura S, Monji A, Sasaki K, Baba S, Onitsuka T, Ohara T, et al.
Neurol Clin Pract . 2018 Feb; 3(4):354-357. PMID: 29473615
No abstract available.
5.
Hayakawa K, Kato T, Watabe M, Teo A, Horikawa H, Kuwano N, et al.
Sci Rep . 2018 Feb; 8(1):2884. PMID: 29440704
Hikikomori, a severe form of social withdrawal syndrome, is a growing social issue in Japan and internationally. The pathophysiology of hikikomori has not yet been elucidated and an effective treatment...
6.
Sato-Kasai M, Kato T, Ohgidani M, Mizoguchi Y, Sagata N, Inamine S, et al.
Schizophr Res . 2016 Sep; 178(1-3):35-43. PMID: 27614570
Viral infections during fetal and adolescent periods, as well as during the course of schizophrenia itself have been linked to the onset and/or relapse of a psychosis. We previously reported...
7.
Watabe M, Kato T, Teo A, Horikawa H, Tateno M, Hayakawa K, et al.
PLoS One . 2015 Apr; 10(3):e0120183. PMID: 25836972
Maladaptive social interaction and its related psychopathology have been highlighted in psychiatry especially among younger generations. In Japan, novel expressive forms of psychiatric phenomena such as "modern-type depression" and "hikikomori"...
8.
Mizoguchi Y, Kato T, Horikawa H, Monji A
Front Cell Neurosci . 2014 Nov; 8:370. PMID: 25414641
Microglia are resident innate immune cells which release many factors including proinflammatory cytokines, nitric oxide (NO) and neurotrophic factors when they are activated in response to immunological stimuli. Recent reports...
9.
Mizoguchi Y, Kato T, Seki Y, Ohgidani M, Sagata N, Horikawa H, et al.
J Biol Chem . 2014 May; 289(26):18549-55. PMID: 24811179
Microglia are immune cells that release factors, including proinflammatory cytokines, nitric oxide (NO), and neurotrophins, following activation after disturbance in the brain. Elevation of intracellular Ca(2+) concentration ([Ca(2+)]i) is important...
10.
Seki Y, Kato T, Monji A, Mizoguchi Y, Horikawa H, Sato-Kasai M, et al.
Schizophr Res . 2013 Oct; 151(1-3):20-8. PMID: 24100191
Recent imaging studies have indicated that the pathophysiology of schizophrenia is closely related to white matter abnormalities and microglial activation. Additionally, recent clinical trials have suggested that atypical antipsychotics may...